JACC:丹麦随访46年研究:中年时心肺功能好,未来寿命长

2018-08-24 xujing 中国循环杂志

近日,丹麦学者开展的随访近半个世纪的研究分析表明,中年时的心肺适能检测显示出良好的心肺功能预示着未来50年内可以活的更久。

近日,丹麦学者开展的随访近半个世纪的研究分析表明,中年时的心肺适能检测显示出良好的心肺功能预示着未来50年内可以活的更久。

研究者对5107名没有血管疾病(CVD)的男性(平均年龄49岁)在他们的工作场所进行了心肺适能检测,测量最大耗氧量(VO2)峰值。

在46年的随访中,4700人(92%)死亡,2149人(42.1%)死于CVD。

研究发现,与VO2峰值低于正常下限者相比,正常偏低者、正常偏高者以及高于正常上限者的寿命分别延长2.1年、2.9年和4.9年。

VO2峰值每增加1 mL/(kg·min),则寿命会增加45天。

在二次分析中,基于血管死亡率的结果与全因死亡率相似。

研究者表示,重要的是,在排除了第一个十年内死亡的361人后的二次分析的结果同样如此,这就减小了在基线存在的任何未知的缩短寿命的疾病的影响。

相关专家在述评中指出,该研究证实了即使最低水平的身体活动的改善即可带来最大的生存获益。

研究表示,常规应用CRF检查,作为一个客观的衡量标准,总好过医生主观询问患者的运动情况。

原始出处:Johan S.R. Clausen, Jacob L. Marott, Andreas Holtermann, et al. Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up. JACC. August 2018

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    2019-06-03 aids222
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    2018-09-23 hbwxf
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    2018-08-26 智智灵药
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    2018-08-24 1e1b8538m79(暂无匿称)

    不错的文章值得拥有

    0

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    2018-08-24 王秀

    学习了,涨知识了!

    0

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    2018-08-24 天地飞扬

    了解一下,谢谢分享!

    0

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    2018-08-24 医者仁心5538

    学习了

    0

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JAMA intern Med:健康成人中臭氧暴露和心肺病理生理机制间的关联

暴露于臭氧中会影响心血管病死亡发生率,但是其中暗含的生物学机制却并不清楚。本文旨在探究臭氧暴露和心肺病理生理机制间的关联。从2014年12月1日到2015年1月31日期间对中国长沙89名健康成年校园工作人员进行观察研究。这种独特的拟实验性设计能够更好的表征暴露于空气污染环境中产生的效果,因为实验者的大部分时间都花在室内环境中。全程监测室内外臭氧浓度以及一氧化碳污染物颗粒,二氧化氮,二氧化硫情况。结

Mayo Clin Proc:心肺功能对降低冠心病风险至关重要

冠心病(CHD)是美国男性的主要死亡原因,心血管健康(CRF)和血液甘油三酯/高密度脂蛋白比值(TG:HDL比)是冠心病死亡的有力预测因子。在最近一期的梅奥诊所诉讼中,两项新研究强调了CRF在继发心血管疾病和死亡风险方面的重要性。这些文章为成年人和儿童中达到中等到高水平的CRF的重要性提供了实质性的证据。

Lancet:散步过程中汽车尾气对老年人群心肺功能的影响

研究发现,即便是短暂的散步过程中吸入的汽车尾气等污染物也会对COPD、心脏病患者以及健康人群的心肺功能造成影响

Heart:婴幼儿采用微创封堵与开放手术进行室间隔缺损封堵的比较

对于pmVSD婴幼儿,与手术封堵相比,微创封堵可降低术后心肺功能受损的发生率。

Chest:运动中的需氧量测定:标准化单一步行测试方案的评估

这项方案可以作为标准6分钟步行试验的修改版而顺利实施,没有严重的不良事件。

JAMA Intern Med:心肺功能可预测远期心血管疾病

发表于《美国医学会杂志·内科学》一项研究表明,青年期的心肺功能水平可预测远期的心脏功能情况。