J Rheumatol:类风湿性关节炎在怀孕期间是否会真的改善?

2018-11-07 xiangting MedSci原创

60%的RA患者在妊娠期间疾病活动性有所改善, 46.7%的患者产后出现急性发作。

这项研究使用客观的疾病活动性评分系统进行系统评价和meta分析,以评估妊娠期间类风湿性关节炎(RA)的疾病活动性。

研究人员对PubMed、EMBASE/Medline、Cochrane和LactMed数据库进行了系统回顾。分析的纳入标准是前瞻性研究,每项研究超过5名患者,以及有临床医师/健康专业人员使用客观评分系统对RA评估的数据。

10项研究入选最终的分析,共包括237名患者,其中204名患者有可用的产前数据。135次妊娠记录了产后的疾病活动性。

60%的RA患者在妊娠期间疾病活动性有所改善, 46.7%的患者产后出现急性发作。

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    2018-11-09 lmm397
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