Circ Cardiovasc Imaging:经胸三维超声心动图测量的右心室射血分数预后价值如何?

2017-02-20 xing.T MedSci原创

由此可见,3DTTE确定的右心室射血分数与不同背景的患者心脏预后独立相关。3DRVEF为临床危险因素和其他包括预测未来不良结局的左室收缩和舒张功能的超声参数提供了增量价值。

心脏磁共振是评价右心室体积的金标准,但它在每一个病人进行是不切实际的。虽然通过经胸三维超声心动图(3DTTE)得到的右心室容积和右心室射血分数的参考值已经确立,但其预后价值尚未阐明。最近,心血管领域权威杂志Circulation-Cardiovascular Imaging上发表了一篇研究文章,研究人员推测通过3DTTE(3DRVEF)测得的右心室射血分数可以预测未来的心血管事件。

在方案1中,研究人员在60名受试者中确定了3DTTE测量右心室容积和右心室射血分数的准确性,并与心脏磁共振进行比较。在方案2中,为446例各种心血管疾病患者进行了3DRVEF检查。研究对象随访至记录到心源性死亡和主要心血管不良事件。

在方案1中,3DTTE测定的右心室舒张末期容积、收缩末期容积以及右心室射血分数与通过心脏磁共振检查的患者具有良好的相关性(r=0.74–0.90)。在方案2中,在中位随访4.1年期间,有38例心源性死亡和88例主要心血管不良事件发生。单变量Cox比例回归分析显示,3DRVEF与心源性猝死(P<0.0001)和主要不良心血管事件(P<0.0001)相关。即使在逐步多变量Cox比例风险分析中,3DRVEF仍为心源性死亡(P<0.0001)和主要不良心血管事件(P<0.0001)的独立预测因子。分类和回归树分析表明3DRVEF在危险分层中发挥着重要作用。

由此可见,3DTTE确定的右心室射血分数与不同背景的患者心脏预后独立相关。3DRVEF为临床危险因素和其他包括预测未来不良结局的左室收缩和舒张功能的超声参数提供了增量价值。

原始出处:

Yasufumi Nagata,et al. Prognostic Value of Right Ventricular Ejection Fraction Assessed by Transthoracic 3D Echocardiography. Circ Cardiovasc Imaging. 2017. https://doi.org/10.1161/CIRCIMAGING.116.005384

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    2017-12-25 quxin068
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