慢性心力衰竭“新四联”药物治疗临床决策路径专家共识

2022-09-16 中国循环杂志 中国循环杂志

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慢性心力衰竭“新四联”药物治疗临床决策路径专家共识

中国慢性心力衰竭(心衰)患病率持续上升,对民众健康造成极大危害。大型临床研究结果证实,血管紧张素受体脑啡肽酶抑制剂(ARNI)或血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗剂、钠-葡萄糖共转运蛋白2抑制剂(SGLT2i)、β受体阻滞剂和盐皮质激素受体拮抗剂为基础的“新四联”规范化心衰药物治疗模式,能够大幅度改善射血分数降低的心衰患者预后。而SGLT2i和ARNI能够显著改善射血分数保留的心衰患者预后。

本共识提出简洁明了的慢性心衰药物治疗临床决策路径,着重阐述“新四联”药物的启动顺序、启动时机、使用剂量及调整原则、临床注意事项等,强调对慢性心衰患者院内-院外的全程、长期管理,以促进广大临床医师更规范地应用改善心衰预后药物,以期降低中国慢性心衰患者的住院率和死亡率,减轻心衰所造成的社会经济负担。

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    2022-09-16 ms4000001114161496

    好!

    0

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    2022-09-16 ms4000001114161496

    写的真好!

    0

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Cardiovasc Diabetol:恩格列净对稳定性慢性心力衰竭患者酮体水平的影响

稳定型CHF患者服用恩格列嗪后酮体增加。这一增加导致恩格列嗪对血压和血管参数的有益作用减弱。

Cardiovasc Diabetol:卡格列净对2型糖尿病和慢性心力衰竭患者N端脑钠肽前体的影响

二甲双胍长期以来被广泛应用,是治疗2型糖尿病(T2D)已确定的基础降糖药物。

POLM:生脉饮通过调节亚油酸代谢对慢性心力衰竭的心脏保护作用

深入研究生脉饮治疗慢性心力衰竭的机制,为临床应用提供指导。

推荐阅读:慢性心力最新衰竭“新四联”药物治疗临床决策路径专家共识

本共识提出简洁明了的慢性心衰药物治疗临床决策路径,着重阐述“新四联”药物的启动顺序、启动时机、使用剂量及调整原则、临床注意事项等,强调对慢性心衰患者院内-院外的全程、长期管理