UROLOGY:炎性尿道狭窄的延迟重建与多重干预、更长的狭窄和更复杂的修复有关

2018-02-23 MedSci MedSci原创

在尿道重建之前,许多狭窄的患者经历了一个可复性周期,在此期间内视镜治疗是为了治疗复发性的阻塞性症状。研究人员评估了尿道成形术延迟、内镜治疗和随后的重建结果之间的关系。

目的
在尿道重建之前,许多狭窄的患者经历了一个可复性周期,在此期间内视镜治疗是为了治疗复发性的阻塞性症状。研究人员评估了尿道成形术延迟、内镜治疗和随后的重建结果之间的关系。

材料和方法
研究人员回顾了从2007年到2014年经历了原发性延髓性尿道成形术的男性的记录。那些有前尿道成形术、阴茎和/或膜性狭窄和不完整数据的患者被排除在分析之外。男性因尿道成形术延迟小于5、5到10或大于10年分为3组。

结果
对278例原发性输尿管成形术患者的完整资料进行了评价。诊断与重建之间的中位时间为5年(IQR 2-10)。病人接受了平均0.9±2.4±SD内镜程序每年的延迟。相对于少于5和5到10年的延迟大于10年与内镜治疗(平均1和2和5),重复自扩(13% vs 14% vs 34%),狭窄超过2厘米(40% vs 39% vs 56%)和复杂的重建技术(17% vs 17% vs 34%)。越来越多的内镜治疗与2 cm以上(或1.06,p = 0.003)的狭窄程度无关,与较短的狭窄(83% vs 96%, p = 0.0003)相比,24个月无狭窄的生存率更低。每个连续的直视内尿道切开术与尿道成形术失败的风险是独立的(HR 1.19, p = 0.02)。

结论
尿道成形术的延迟康复是常见的,常伴有重复尿道损伤的症状性事件。内镜治疗似乎延长了狭窄,增加了修复的复杂性。

原始出处:

Boyd R. Viers.et al.Delayed Reconstruction of Bulbar Urethral Strictures is Associated with Multiple Interventions, Longer Strictures and More Complex Repairs
.UROLOGY.2018.

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    2018-09-02 lifestar
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  3. [GetPortalCommentsPageByObjectIdResponse(id=1769120, encodeId=d1271e6912001, content=<a href='/topic/show?id=ebef4e52844' target=_blank style='color:#2F92EE;'>#尿道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47528, encryptionId=ebef4e52844, topicName=尿道)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b63c37986505, createdName=lifestar, createdTime=Sun Sep 02 14:25:00 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694765, encodeId=f39a1694e654a, content=<a href='/topic/show?id=d4854e544bd' target=_blank style='color:#2F92EE;'>#尿道狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47544, encryptionId=d4854e544bd, topicName=尿道狭窄)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Fri Oct 26 21:25:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=290778, encodeId=45f2290e78fe, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/17/cfa76f1048392033b44c71e9bcb628d9.jpg, createdBy=096c2156900, createdName=梦想起航ing, createdTime=Sun Feb 25 09:53:55 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-02-25 梦想起航ing

    学习了.谢谢分享

    0