Clin Gastroenterol H:吞咽困难的患病率和特征

2019-11-02 xing.T MedSci原创

由此可见,这项基于人群的大型调查揭示吞咽困难较为常见。6名成人中有1名报告了吞咽困难。但是,一半的人尚未与临床医生讨论其症状,许多人可能患有可治愈的疾病。

尽管吞咽困难很常见,但关于吞咽困难的患病率和疾病负担的信息十分有限。近日,消化病领域权威杂志Clinical Gastroenterology and Hepatology发表了一篇研究文章,研究人员对美国31000多名成年人进行了基于人群的调查,以评估吞咽困难患者的流行病学、临床特征和就医行为。

研究人员对美国于2018年4月4日至4月19日进行健康检查并完成在线自我评估的成年人进行了横断面分析。所有受访者都被问及曾经历过以下哪些症状(随机出现):吞咽困难、腹痛、腹胀、失禁、便秘、腹泻、灼热/反流、恶心/呕吐,或以上都不是。只有选择吞咽困难的受访者才继续进行余下的调查,其中包括吞咽困难的严重程度、代偿性行为、寻求医疗保健和食道合并症的问题。

共有31129名参与者参加了调查,其中4998名受访者(16.1%)报告有吞咽困难。其中92.3%在前一周有症状。研究人员发现有16.3%的受访者称在过去7天中他们经历过“有点”或“非常”严重的吞咽困难。喝水有助于吞咽困难(86.0%)和完成进食时间更长(76.5%)是最常见的代偿性行为。总体而言,有51.1%的人因吞咽困难而寻求治疗;老年人、男性、常规护理和保险来源、合并症以及更严重的吞咽困难症状增加了寻求治疗的几率(P<.05)。最常报道的食道合并症是食管反流病(30.9%)、嗜酸性食管炎(8.0%)和食道狭窄(4.5%)。

由此可见,这项基于人群的大型调查揭示吞咽困难较为常见。6名成人中有1名报告了吞咽困难。但是,一半的人尚未与临床医生讨论其症状,许多人可能患有可治愈的疾病。 

原始出处:

Christopher Adkins,et al.Prevalence and Characteristics of Dysphagia Based on a Population-Based Survey.Clinical gastroenterology and hepatology.2019.https://doi.org/10.1016/j.cgh.2019.10.029

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