Lancet:中低收入国家儿童腹泻负担及风险因素研究

2020-05-07 MedSci原创 MedSci原创

通过分析腹泻负担的地理空间趋势及其主要危险因素,研究人员可以评估国家各地区腹泻死亡风险因素,鉴于中低收入国家资源有限,准确地量化腹泻负担及其驱动因素对于精准的公共卫生十分重要

在低收入和中等收入国家中(LMICs),五岁以下儿童中有十分之一死于腹泻。国家间腹泻发病率和死亡率的差异很大,近日研究人员就腹泻负担最重国家的相关危险因素进行了考察。
 
研究人员使用了基于贝叶斯模型数据集,该数据集由94个LMICs的466研究组成,包含15072746名5岁以下儿童,结合2017年全球疾病、伤害和风险因素研究(GBD)的结果,估计2000年至2017年各国腹泻流行率、发病率和死亡率。根据这些数据,研究人员通过空间聚合绘制不同国家以下各级(称为单位)的腹泻负担,并通过创建聚合风险因子估计风险因素。
 
研究发现,腹泻死亡率下降幅度最大的地区是南亚、东南亚和南美洲,分别有54.0%、17.4%和59.5%的单位,腹泻死亡率下降幅度大于10%。尽管非洲大部分地区的儿童仍然面临较高的腹泻致死风险,但死亡人数最多的地区并非非洲,死亡率最高的单位在巴基斯坦。印度尼西亚的国内差异最为显著,部分地区的死亡率几乎是国家平均死亡率的四倍。死亡率的降低与水、卫生和个人卫生(WASH)的改善或儿童生长衰竭(CGF)的减少相关。同样,大多数高危地区的WASH较差、CGF高或口服补液治疗覆盖率低。
 
通过分析腹泻负担的地理空间趋势及其主要危险因素,研究人员可以评估国家各地区腹泻死亡风险因素,鉴于中低收入国家资源有限,准确地量化腹泻负担及其驱动因素对于精准的公共卫生十分重要。
 
原始出处:
 

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2021-04-21 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2020-08-27 14818eb4m67暂无昵称

    学习了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2020-05-07 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

相关资讯

IBD:全反式维甲酸可抵消肠道炎症中的腹泻并抑制腺瘤表达

肠上皮中的Cl- / HCO 3 -交换泵——DRA已成为腹泻的一个重要的治疗靶点,全反式维甲酸(ATRA)是一种关键的维生素A代谢产物,之前曾证明它可以刺激DRA在肠上皮细胞中的表达。因此,本项研

腹泻可能也是新型冠状病毒感染的肺炎首发症状

武汉大学人民医院专家研究发现,感染新型冠状病毒性肺炎后,患者并非一定首先表现为发热和呼吸系统症状,还存在消化系统、神经系统、心血管系统、眼科等症状。武汉大学人民医院1月24日发布《高度重视非呼吸系统的首发症状——新型冠状病毒性肺炎(2019-nCOV)患者的识别与防护》,提醒医护人员及公众,高度警惕以非呼吸系统症状为首发症状的新型肺炎。权威部门日前发布的《关于印发新型冠状病毒感染的肺炎诊疗方案(试

Dig Liver Dis: 功能性慢性水泻患者中粪钙卫蛋白水平可作为微观结肠炎的生物标志物

目前关于使用粪便标志物来进行一些生物学标记的检查还比较少,本项研究旨在评估粪钙卫蛋白是否可以作为微观结肠炎的诊断标志物。

腹痛、腹泻的“凶手”,终于找到了!

引起腹痛、腹泻的原因很多,细菌、病毒、各种肠道疾病等等,而还有这样一种叫蓝氏贾第鞭毛虫的小虫子也不容忽视。

病例:反复腹痛腹泻5年,是胃还是肠?

患者,男性,30岁,反复腹痛腹泻5年。整天胃疼,以晨起和晚上入睡前最严重,经常饭后腹痛、腹泻,腹泻后腹痛消失。药物治疗没什么效果,身体一直消瘦。

Clin Gastroenterol H:腹泻与COVID-19患者症状和病毒携带时间延长有关

SARS-CoV-2肺炎患者中有31%患者出现腹泻。腹泻患者粪便中病毒RNA阳性的比例明显高于无腹泻患者。SARS-CoV-2从粪便中消除比从鼻子和喉咙中消除需要更长的时间。