Gut:绿色地中海饮食可降低50%以上的脂肪肝患病率

2021-01-19 MedSci原创 MedSci原创

非酒精性脂肪肝(NAFLD)俗称脂肪肝,是最常见的慢性肝脏疾病。随着社会经济的发展和人民生活水平的提高,近年来我国脂肪肝发病率极具上升,从18%增加到29.2%。如果不引起重视,脂肪肝可以进一步发展为

非酒精性脂肪肝(NAFLD)俗称脂肪肝,是最常见的慢性肝脏疾病。随着社会经济的发展和人民生活水平的提高,近年来我国脂肪肝发病率极具上升,从18%增加到29.2%。如果不引起重视,脂肪肝可以进一步发展为脂肪性肝炎,肝硬化和肝细胞癌。因此,及早采取预防措施变得尤为重要。

1月19日,发表在Gut杂志的一项长期临床干预研究表明,与其他类型健康饮食相比,绿色地中海饮食能极大程度的减少肝内脂肪累积,降低50%的NAFLD患病率。

在这项为期18个月的DIRECT-PLUS随机临床试验中,研究人员收纳了来自以色列内盖夫核研究中心294名腹部肥胖/血脂异常的参与者,并随机分配到健康饮食组,地中海饮食组和绿色地中海饮食组。绿色地中海饮食是在地中海饮食上增加了440毫克/天的多酚的食物,比如绿茶(3-4杯/天)和Mankai冻奶昔(100克/天)。Mankai冻奶昔富含天然有效蛋白、铁、B12、维生素、矿物质和多酚等。另外,在绿色地中海饮食中还限制在加工肉和红肉的摄入量。健康饮食组接受了标准的营养咨询,以促进健康饮食,并达到类似的干预强度。所有组的参与者均进行体育锻炼。研究人员通过质子磁共振波谱(MRS)连续测定了肝内脂肪比例的变化。

结果显示,在经过18个月生活干预后,所有参与者的NAFLD患病率均有所下降,绿色地中海饮食显著下降,NAFLD患病率从基线时的62%下降到31.5%。而地中海饮食组和健康饮食组分别下降到47.9%和54.8%。在所有饮食方案中。肝内脂肪都有所减少,绿色地中海饮食显著减少了肝内脂肪的累积高达38.9%,而地中海饮食减少比例为19.6%,健康饮食减少比例为12.2%。同时,相比于健康饮食,绿色地中海饮食和地中海饮食参与者体重均有明显下降。

干预18个月后,体重和肝内脂肪的变化

肝内脂肪与肠道微生物组的关系

另外,在地中海饮食和绿色地中海饮食组中,血浆中总多酚水血清叶酸水平平均显着高于健康饮食组,且在绿色地中海饮食组检测到了多酚类物质,而且三组中所有参与者,血清叶酸水平均有所升高,在绿色地中海饮食组血清叶酸水平显著增加。Mankai和核桃的摄入增加与肝内脂肪减少比例显著相关。

总之,绿色地中海饮食富含的多酚,并减少红肉/加工肉的摄入,不仅减轻了体重,还能显著减少肝脏脂肪。同时这项研究提示,饮食方案在预防NAFLD的重要作用。

原始出处

Anat Yaskolka Meir,Ehud Rinott,Gal Tsaban. et al.Effect of green-Mediterranean diet on intrahepatic fat: the DIRECT PLUS randomised controlled trial .Gut.2021

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    2021-06-15 ms3000000239920607

    冻奶昔是什么?

    0

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    2021-02-17 营养医师

    第一段是急剧,不是极具

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=973606, encodeId=ac919e360660, content=冻奶昔是什么?, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f8185520887, createdName=ms3000000239920607, createdTime=Tue Jun 15 00:02:52 CST 2021, time=2021-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925065, encodeId=10f692506592, content=第一段是急剧,不是极具, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3e502075746, createdName=营养医师, createdTime=Wed Feb 17 15:24:39 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1025884, encodeId=380310258843a, content=地中海饮食是热点,被认为是最健康的饮食,而中国传统饮食一般被认为多半是不健康的,这是事实吗?其实需要更多严谨的科学证据,而不是猜测!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健康达人, createdTime=Fri Jan 22 17:41:16 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250724, encodeId=abef1250e246e, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Thu Jan 21 08:41:16 CST 2021, time=2021-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575537, encodeId=365f15e5537bc, content=<a href='/topic/show?id=cd9941326bc' target=_blank style='color:#2F92EE;'>#地中海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41326, encryptionId=cd9941326bc, topicName=地中海)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=303116130321, createdName=wgx311, createdTime=Thu Jan 21 08:41:16 CST 2021, time=2021-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918473, encodeId=72019184e3c1, content=绿茶喝起来!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ddef5453803, createdName=kun, createdTime=Wed Jan 20 17:03:14 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918377, encodeId=554d9183e73a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb355252510, createdName=147e4706m08暂无昵称, createdTime=Wed Jan 20 13:52:25 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918329, encodeId=ed05918329ae, content=<a href='/topic/show?id=f7a410415815' target=_blank style='color:#2F92EE;'>#绿色地中海饮食#</a>可降低超过50%的脂肪肝患病率,绿色地中海饮食是在地中海饮食上增加了440毫克/天的多酚的食物,比如绿茶(3-4杯/天)和Mankai冻奶昔(100克/天)。Mankai冻奶昔富含天然有效蛋白、铁、B12、维生素、矿物质和多酚等。 绿茶和红茶都要喝起来。, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104158, encryptionId=f7a410415815, topicName=绿色地中海饮食)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 11:49:57 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-01-22 健康达人

    地中海饮食是热点,被认为是最健康的饮食,而中国传统饮食一般被认为多半是不健康的,这是事实吗?其实需要更多严谨的科学证据,而不是猜测!

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=973606, encodeId=ac919e360660, content=冻奶昔是什么?, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f8185520887, createdName=ms3000000239920607, createdTime=Tue Jun 15 00:02:52 CST 2021, time=2021-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925065, encodeId=10f692506592, content=第一段是急剧,不是极具, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3e502075746, createdName=营养医师, createdTime=Wed Feb 17 15:24:39 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1025884, encodeId=380310258843a, content=地中海饮食是热点,被认为是最健康的饮食,而中国传统饮食一般被认为多半是不健康的,这是事实吗?其实需要更多严谨的科学证据,而不是猜测!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健康达人, createdTime=Fri Jan 22 17:41:16 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250724, encodeId=abef1250e246e, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Thu Jan 21 08:41:16 CST 2021, time=2021-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575537, encodeId=365f15e5537bc, content=<a href='/topic/show?id=cd9941326bc' target=_blank style='color:#2F92EE;'>#地中海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41326, encryptionId=cd9941326bc, topicName=地中海)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=303116130321, createdName=wgx311, createdTime=Thu Jan 21 08:41:16 CST 2021, time=2021-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918473, encodeId=72019184e3c1, content=绿茶喝起来!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ddef5453803, createdName=kun, createdTime=Wed Jan 20 17:03:14 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918377, encodeId=554d9183e73a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb355252510, createdName=147e4706m08暂无昵称, createdTime=Wed Jan 20 13:52:25 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918329, encodeId=ed05918329ae, content=<a href='/topic/show?id=f7a410415815' target=_blank style='color:#2F92EE;'>#绿色地中海饮食#</a>可降低超过50%的脂肪肝患病率,绿色地中海饮食是在地中海饮食上增加了440毫克/天的多酚的食物,比如绿茶(3-4杯/天)和Mankai冻奶昔(100克/天)。Mankai冻奶昔富含天然有效蛋白、铁、B12、维生素、矿物质和多酚等。 绿茶和红茶都要喝起来。, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104158, encryptionId=f7a410415815, topicName=绿色地中海饮食)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 11:49:57 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-01-21 wgx311
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    2021-01-20 kun

    绿茶喝起来!

    0

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    2021-01-20 147e4706m08暂无昵称

    学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=973606, encodeId=ac919e360660, content=冻奶昔是什么?, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f8185520887, createdName=ms3000000239920607, createdTime=Tue Jun 15 00:02:52 CST 2021, time=2021-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=925065, encodeId=10f692506592, content=第一段是急剧,不是极具, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3e502075746, createdName=营养医师, createdTime=Wed Feb 17 15:24:39 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1025884, encodeId=380310258843a, content=地中海饮食是热点,被认为是最健康的饮食,而中国传统饮食一般被认为多半是不健康的,这是事实吗?其实需要更多严谨的科学证据,而不是猜测!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健康达人, createdTime=Fri Jan 22 17:41:16 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250724, encodeId=abef1250e246e, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Thu Jan 21 08:41:16 CST 2021, time=2021-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575537, encodeId=365f15e5537bc, content=<a href='/topic/show?id=cd9941326bc' target=_blank style='color:#2F92EE;'>#地中海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41326, encryptionId=cd9941326bc, topicName=地中海)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=303116130321, createdName=wgx311, createdTime=Thu Jan 21 08:41:16 CST 2021, time=2021-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918473, encodeId=72019184e3c1, content=绿茶喝起来!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ddef5453803, createdName=kun, createdTime=Wed Jan 20 17:03:14 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918377, encodeId=554d9183e73a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb355252510, createdName=147e4706m08暂无昵称, createdTime=Wed Jan 20 13:52:25 CST 2021, time=2021-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918329, encodeId=ed05918329ae, content=<a href='/topic/show?id=f7a410415815' target=_blank style='color:#2F92EE;'>#绿色地中海饮食#</a>可降低超过50%的脂肪肝患病率,绿色地中海饮食是在地中海饮食上增加了440毫克/天的多酚的食物,比如绿茶(3-4杯/天)和Mankai冻奶昔(100克/天)。Mankai冻奶昔富含天然有效蛋白、铁、B12、维生素、矿物质和多酚等。 绿茶和红茶都要喝起来。, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104158, encryptionId=f7a410415815, topicName=绿色地中海饮食)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Jan 20 11:49:57 CST 2021, time=2021-01-20, status=1, ipAttribution=)]
    2021-01-20 Jessica

    #绿色地中海饮食#可降低超过50%的脂肪肝患病率,绿色地中海饮食是在地中海饮食上增加了440毫克/天的多酚的食物,比如绿茶(3-4杯/天)和Mankai冻奶昔(100克/天)。Mankai冻奶昔富含天然有效蛋白、铁、B12、维生素、矿物质和多酚等。 绿茶和红茶都要喝起来。

    0

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