Heart:顽固性高血压的全球患病率

2018-08-08 xing.T MedSci原创

由此可见,该研究显示真顽固性高血压的患病率很高。这种患病率低于明显治疗顽固性高血压,表明使用动态血压测量排除包括白大衣高血压在内的假顽固性高血压的重要性。慢性肾病患者的顽固性高血压负担最高。考虑到疾病的灾难性并发症,急需新的治疗顽固性高血压的方法。

近日,心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员进行了一次系统评价和荟萃分析旨在评估全球高血压患者中明显治疗顽固性、假顽固性和真顽固性高血压的具体患病率。

研究人员检索了PubMed、EMBASE、Web of Science和Global Index Medicus等数据库,以确定从数据库成立到2017年9月30日期间发表的文章,并检索了文章的参考列表。研究人员使用随机效应模型来估计研究中顽固性高血压的患病率,并通过Cochran Q统计量的χ2检验来评估研究的异质性。

研究人员纳入了1991年至2017年期间发表的91项研究,报告了全球抗高血压药物治疗的3207911例高血压患者的汇总样本数据。大多数研究(n=64,70%)仅使用了诊室血压(BP)指标。在一般情况下,接受治疗的高血压患者人群中,真顽固性、明显治疗顽固性和假顽固性高血压的患病率分别为10.3%(95%CI为7.6%-13.2%)、14.7%(95%CI为13.1%-16.3%)和10.3%(95%CI为6.0%-15.5%)。慢性肾病、肾移植和老年患者发生真顽固性高血压的患病率分别为22.9%(95%CI为19.1%-27.0%)、56.0%(95%CI 为52.7%-59.3%)和12.3%(95%CI为1.7%-30.5%)。

由此可见,该研究显示真顽固性高血压的患病率很高。这种患病率低于明显治疗顽固性高血压,表明使用动态血压测量排除包括白大衣高血压在内的假顽固性高血压的重要性。慢性肾病患者的顽固性高血压负担最高。考虑到疾病的灾难性并发症,急需新的治疗顽固性高血压的方法。

原始出处:

Jean Jacques Noubiap,et al. Global prevalence of resistant hypertension: a meta-analysis of data from 3.2 million patients. Heart. 2018. http://dx.doi.org/10.1136/heartjnl-2018-313599

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    2018-08-10 zhaojie88
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    2018-08-10 slcumt
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    2018-08-08 易水河

    高血压人群越来越多

    0

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    2018-08-08 sunfeifeiyang

    0

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    2018-08-08 flysky120

    顽固性高血压的治疗呢?

    0

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    2018-08-08 13718711b3m

    学习了,获益匪浅,感谢分享,涨知识

    0

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