European Radiology:静音MRA为脑动静脉畸形的评估提供了新的指标

2022-01-19 shaosai MedSci原创

脑动静脉畸形(BAVM)是一种常见脑血管发育畸形,表现为动脉与静脉之间无毛细血管网而直接相连。BAVM的主要治疗方式包括手术、外科和血管内治疗。

脑动静脉畸形(BAVM)是一种常见血管发育畸形表现为动脉与静脉之间无毛细血管网而直接相连。BAVM的主要治疗方式包括手术、外科和血管内治疗。以往的研究表明,带有高流量动静脉(A-V)分流的BAVM与围手术期出血事件的增加和不完全闭塞的风险较高有关。因此在手术切前,对BAVM的高流量A-V分流进行准确识别和定向栓塞是血管内治疗的关键。

数字减影血管造影(DSA)由于其高空间和时间分辨率,是评估高流量A-V分流的金标准。然而,DSA是一种侵入性检查,具有不可避免的手术相关并发症的风险,因此不适用于连续的后续检查。

静音MR血管成像是一种基于动脉自旋标记(ASL)和ZTE技术的新兴成像方法。一些研究报告称,与TOF MR血管成像相比,静音MRA在描绘BAVM的病灶和引流静脉方面较果更佳

近日,发表在European Radiology杂志的一项研究探讨了静音MRA计算的引流静脉强度(SI)比值与DSA测量的动静脉转运时间之间的关系以及静音MRA上具有最大rSI的引流静脉的特征与出血表现之间的关系BAVM高流量A-V分流提供有价值的影像学参考指标

本研究对46名接受静音MRA和DSA的BAVM患者(平均年龄33.2±16.9岁)的81条引流静脉进行了回顾性评估。研究了静音MRA上引流静脉的rSI与DSA上A-V转运时间之间的相关性。同时生成AUC-ROC以评估rSI在确定是否存在高流量A-V分流的性能。进一步比较了出血性和非出血性未经治疗的BAVM之间具有最大rSI(rSImax)的引流静脉的特征。 

静音MRA上各引流静脉的rSI与DSA的A-V转运时间明显相关(r = -0.81,p < .001)。使用rSI确定高流量A-V分流的AUC-ROC为0.89。rSI的临界值为1.09,其敏感性为82.4%,特异性为82.8%。出血组的引流静脉具有rSImax且没有异位的情况明显更多(P = 0.045)。 

 64岁男性左颞部BAVM的图像,有几条的引流静脉向上矢状窦、乙状窦和直窦方向延伸。 a 静音MR血管造影的三维MIP显示一条扩张的引流静脉(红色箭头)和一条小的引流静脉(红色长箭头)。请注意,在DSA上描绘出病灶后四帧以上观察到的几条引流静脉(黑色箭头),在静音MRA上是看不到的。

本研究表明静音MRA测量的引流静脉SI比率与DSA上BAVM的动静脉转运时间具有相关性静音MRA上的rSI可作为评估BAVM高流量A-V分流的潜在影像学标志物。

原文出处

Chun-Xue Wu,Zhen-Xiang Zang,Tao Hong,et al.Signal intensity ratio of draining vein on silent MR angiography as an indicator of high-flow arteriovenous shunt in brain arteriovenous malformation.DOI:10.1007/s00330-021-08170-8

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    2022-03-07 feather89
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    2022-09-09 fusion
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    2022-01-22 ms2000001540243701

    学习

    0

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    2022-01-21 wushaoling
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    2022-01-21 FukaiBao

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