J Periodontol:血小板指数与冠心病患者牙周炎相关性的初步研究

2018-10-05 MedSci MedSci原创

牙周炎与冠状动脉疾病(CAD)之间关系的机制一直是研究的焦点。本研究旨在检验牙周炎症表面积(PISA)值与CAD患者全血参数的关系。

牙周炎与冠状动脉疾病(CAD)之间关系的机制一直是研究的焦点。本研究旨在检验牙周炎症表面积(PISA)值与CAD患者全血参数的关系。

方法:研究纳入30-75岁怀疑患有冠心病的冠状动脉造影的患者。记录临床牙周参数(探诊深度[PD],临床附着丧失,探诊出血),冠状动脉造影后将参与者分为4组:第1组:CAD(+)伴牙周炎(n = 20),组2:没有牙周炎的CAD(+)(n = 20),组3:患有牙周炎的CAD( - )(n = 21),组4:没有牙周炎和CAD( - )(n = 16)。分析了所研究参数之间的差异和相关性的全血细胞计数。

结果:CAD(+)P(+)个体的血小板分布宽度(PDW)值显着高于其他组(P <0.0125)。在整个研究组中,PISA评分与平均血小板体积(MPV,P = 0.021,rho = 0.264),PISA和PDW(P = 0.240,rho = 0.036)之间存在正相关性较低的相关性;发现伴有/不伴有牙周炎的CAD( - )组中PD与红细胞分布宽度(RDW,P = 0.049,rho = 0.445)之间存在中度相关性。发现年龄预测CAD时OR较低(1.17,P <0.01)。

本研究根据炎症性疾病及其与PISA值的显着低和中度相关性之间的关系,突出了有/无牙周炎的CAD患者的一些血液参数(PDW,RDW和MPV)。

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    2018-12-05 feather89
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    2018-10-07 flysky120

    学习血小板关联知识

    0

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    2018-10-05 医者仁心5538

    学习了

    0

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J Clin Periodontol: 唾液和血清标志物在牙周炎和冠心病中的应用

基质金属蛋白酶(MMP)-8,MMP-9,基质金属蛋白酶组织抑制剂(TIMP)-1和髓过氧化物酶(MPO)参与牙周组织和动脉粥样硬化斑块的细胞外基质分解。我们调查了血清和唾液生物标志物在牙周炎和急性冠状动脉综合征(ACS)中的诊断价值。

2018 SIGN国家临床指南:冠心病心律失常(152)

2018年9月,苏格兰校际指南网络(SIGN)发布了冠心病心律失常指南,冠心病与多种心律失常相关,急性冠脉综合征期间常见心律失常,室性心律失常是心跳骤停和心脏性猝死的主要原因,慢性冠心病患者,尤其是左心功能不全以及心力衰竭患者也有长期室性心律失常以及心脏性猝死的风险,本文主要针对冠心病相关心跳骤停和心律失常的关提供循证指导建议。

JAHA:心血管危险因素对女性冠心病和卒中的影响

心血管危险因素对心血管疾病的各种表现有不同的影响,但到目前为止,直接进行比较较少见,且主要在男性中比较。本研究纳入比较了1731名心血管疾病的女性与1914名正常的女性,发现24大危险因素(包括各种载脂蛋白、血红蛋白A1C、高灵敏度C反应蛋白、N末端脑钠肽和组织纤溶酶原激活物抗原)的作用方向在冠心病(CHD)和缺血性卒中中是一致的,但在CHD中相关性更强。当比较出血性脑卒中与缺血性脑卒中的疗效时,

理气活血滴丸治疗冠心病稳定型心绞痛中国专家共识

为提高理气活血滴丸防治冠心病稳定型心绞痛的水平,规范其在冠心病稳定型心绞痛中的应用,中国中西医结合学会心血管病专业委员会组织相关专家,以传统中医辨证论治为基本点,对其药理作用和现有临床有效性、安全性数据进行了系统回顾分析和总结,并讨论起草了《理气活血滴丸治疗冠心病稳定型心绞痛中国专家共识》。本共识仅根据现有研究证据和专家经验形成,旨在为临床用药提供参考,但并非医疗行为标准或规范,随着临床实践发展以

血管紧张素Ⅱ受体拮抗剂在冠心病患者中的临床应用建议(2018)

为整体提升临床医师对RAASi 在冠心病患者中的规范化使用,提高临床医师对ARB 的认识,针对ARB 用于治疗冠心病患者的临床建议具有较大的实践指导意义。因此,撰写《血管紧张素Ⅱ受体拮抗剂在冠心病患者中的临床应用建议》非常必要。