Diabetic Med:糖尿病对慢性全身闭塞经皮冠状动脉介入治疗急性结局的影响

2017-07-06 MedSci MedSci原创

近日,国际杂志 《Diabetic medicine》上在线发表一项美国多中心登记册的观察性研究,探讨糖尿病对慢性全身闭塞经皮冠状动脉介入治疗急性结局的影响。

近日,国际杂志 《Diabetic medicine》上在线发表一项美国多中心登记册的观察性研究,探讨糖尿病对慢性全身闭塞经皮冠状动脉介入治疗急性结局的影响。

研究人员评估了2012年至2015年期间,在美国11个中心接受此类手术的1308人中糖尿病对经皮冠状动脉介入治疗慢性完全闭塞的结果的影响。

参加者的平均± SD年龄为66±10岁,84%为男性,44.6%患有糖尿病。与没有糖尿病的参与者相比,糖尿病患者更有可能接受冠状动脉旁路移植手术(38 vs 31; P = 0.006),先前有心力衰竭(35 vs 22; P = 0.0001),外周动脉疾病(19vs13; P = 0.002)。此外,他们还具有较高的BMI31±6kg / m2 vs 29±6kg / m2 ;P = 0.001),相似的日本慢性总闭塞评分(2.6±1.2vs 2.5±1.2;P = 0.82),相似的成功交叉技术:顺行线升高(46 vs 47; P = 0.66),逆行(30vs28; P = 0.66)和顺行解剖重新进入(24vs25; P = 0.66)。两组的技术指标(91vs90; P = 0.80)和手术(89 vs 89; P = 0.93)成功率相似,主要不良心脏事件发生率(2.2 vs 2.5; P = 0.61) 。

研究表明,在经历冠状动脉介入治疗慢性完全闭塞的现代人群中,近一半(45%)患有糖尿病。糖尿病患者和非糖尿病患者的手术成功率和并发症发生率相似。

原始出处:

J. R. Martinez-Parachini, A. Karatasakis, D. Karmpaliotis,et al. Impact of diabetes mellitus on acute outcomes of percutaneous coronary intervention in chronic total occlusions: insights from a US multicentre registry

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