JAMA Intern Med:75-79岁老年糖尿病患者胰岛素使用与停药率

2019-09-24 MedSci MedSci原创

研究发现,对于患有II型糖尿病的老年患者,其自身健康状态与胰岛素的使用率相关,部分健康状态良好人群在75岁以后可停止胰岛素使用

近日,研究人员考察了健康状况不佳的老年人与健康状况良好的老年人相比,胰岛素治疗的使用频率和停药频率差异。

21531名II型糖尿病患者,从75岁开始,随访时间长达4年。健康状况被定义为良好(<2种共患病或2种共患病但可进行体力活动)、中度(>2种共患病或2种共患病且自我报告未进行每周锻炼),或不良(有终末期肺、心脏或肾脏疾病,痴呆诊断或转移性癌症)。研究的主要终点为胰岛素使用率及停药率。

21531例患者中,女性10396例(48.3%),平均年龄75岁,近五分之一(4076人[18.9%])使用胰岛素。与健康状态良好人群相比,不良及中等人群,75岁胰岛素使用风险增加(aRR,2.03和1.85)。32.7%的胰岛素使用者在入组后4年内停止使用胰岛素。健康状况不良(aRR 1.47)和中等(aRR 1.16)个体继续使用胰岛素的可能性更高。

研究发现,对于患有II型糖尿病的老年患者,其自身健康状态与胰岛素的使用率相关,部分健康状态良好人群在75岁以后可停止胰岛素使用。

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    2020-08-07 baoya
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    2019-09-26 yinhl1980
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    2019-09-24 misszhang

    谢谢MedSci提供最新的资讯

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