BMJ:普及富钾食盐可大幅降低中国心血管死亡风险

2020-04-25 MedSci原创 MedSci原创

中国全国范围内的富钾食盐替代将带来可观的净效益,总体上可减少约九分之一的心血管疾病死亡。

近日研究人员考察了在全国范围内推广高钾食盐对心血管疾病发病率和死亡率的影响。
 
本次研究为模型研究,研究群体为中国成年人口,特别是1700万慢性肾病患者,采用比较风险评估模型评估全国范围内用富钾食盐(20-30%氯化钾)替代膳食盐的干预效果。研究对的主要终点是在实施富钾食盐替代后,因心血管疾病、非致命事件和因血压事件风险下降而导致的调整后的死亡人数。在患有慢性肾脏疾病的个体中,计算了因钾摄入量增加引起的高钾血症,以及心血管疾病的额外死亡。
 
在全国范围内实施富钾盐后,每年可减少心血管疾病死亡约461000人,相当于中国每年心血管疾病死亡人数的11.0%,每年可减少非致命性心血管事件743000起 以及每年790万与心血管疾病相关的残疾调整寿命年,但这种干预可能会在慢性肾脏疾病患者中产生约11000与高钾血症有关的额外死亡。其净影响是,在总人口中,每年死于心血管疾病的人数将减少约450000,慢性肾病患者的死亡人数将减少21000。在敏感性分析中,总人口和慢性肾脏病患者的净收益是一致的,避免的死亡超过额外死亡。
 
据估计,中国全国范围内的富钾食盐替代将带来可观的净效益,总体上可减少约九分之一的心血管疾病死亡。
 
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    2021-06-24 12192b1am98暂无昵称

    学习了

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    2020-07-31 gaoxiaoe
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    2020-04-27 lingqf
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