J Asthma Allergy:一项评估中国儿童过敏性鼻炎风险因素和气源性致敏原过敏特征的多中心研究

2022-01-15 AlexYang MedSci原创

对临床AR的致敏模式和风险因素的最新信息进行了评估,以制定预防和治疗AR的有效策略。

到目前为止,关于过敏性鼻炎(AR)的流行病学研究主要集中在确定中国成年人的患病风险,其中大部分是由单个中心设计的,而描述自我报告AR儿童的过敏横断面和流行病学数据很少

近期,来自广州医科大学的研究人员在《J Asthma Allergy》上发表文章,他们对临床AR的致敏模式和风险因素的最新信息进行了评估,以制定预防和治疗AR的有效策略

在2020年1月至2021年6月期间,研究人员进行了一项横断面调查,涉及中国7个城市报告AR的儿童。共有762名儿童参加了此次调查。通过问卷调查和对11种气源性过敏原的特异性免疫球蛋白E的调查,评估了临床AR的风险因素和特定的致敏模式。

在762名患者中,593名(77.8%)至少有一个IgE阳性水平。7-14岁(OR 1.503,(95% CI 1.058-2.136),P=0.023);患有过敏性结膜炎(OR 1.843,(95% CI 1.297-2.620),P=0.001)和居住在东部(OR 1.802,(95% CI 1.263-2.573),P = 0.001)均与较高的气源性过敏原相关的临床AR风险有关。在0-6岁和7-14岁年龄组中,D. pteronyssinus和D. farinae的致敏率高于其他过敏原。在东部地区报告的AR儿童中,最常见的空气过敏原是D. farinae(74.9%)和D. pteronyssinus(74.3%),而在西部地区则是艾蒿(60.0%)和Marguerite(56.6%)。西部地区大多数sIgE阳性受试者对三种或三种以上的测试花粉过敏原过敏(52.1%),而东部地区只有5.7%。

临床AR的风险因素

综上所述,中国儿童的过敏症存在明显的地域差异。年龄对儿童的过敏原致敏率也有很大影响,但这些影响在不同地区有所不同

原始出处:

Liting Wu , Wenting Luo , Haisheng Hu et al. A Multicenter Study Assessing Risk Factors and Aeroallergens Sensitization Characteristics in Children with Self-Reported Allergic Rhinitis in China. J Asthma Allergy. Dec 2021

 

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    2022-09-08 zutt
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    2022-12-09 skhzy
  7. [GetPortalCommentsPageByObjectIdResponse(id=1904108, encodeId=6fb5190410845, content=<a href='/topic/show?id=7d454302945' target=_blank style='color:#2F92EE;'>#多中心#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43029, encryptionId=7d454302945, topicName=多中心)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Mar 17 01:24:07 CST 2022, time=2022-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2069458, encodeId=177e2069458ca, content=<a href='/topic/show?id=c4ad28491a8' target=_blank style='color:#2F92EE;'>#儿童过敏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28491, encryptionId=c4ad28491a8, topicName=儿童过敏)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Thu Sep 08 06:24:07 CST 2022, time=2022-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1713000, encodeId=c7c61e13000b4, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Tue Aug 02 22:24:07 CST 2022, time=2022-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2047459, encodeId=c69c204e45921, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Fri Dec 30 07:24:07 CST 2022, time=2022-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909522, encodeId=c1dc190952223, content=<a href='/topic/show?id=16c6430324c' target=_blank style='color:#2F92EE;'>#多中心研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43032, encryptionId=16c6430324c, topicName=多中心研究)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85aa264, createdName=redcrab, createdTime=Fri Aug 12 11:24:07 CST 2022, time=2022-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977184, encodeId=3c0c19e71845a, content=<a href='/topic/show?id=0081289832' target=_blank style='color:#2F92EE;'>#asthma#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2898, encryptionId=0081289832, topicName=asthma)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b30126, createdName=skhzy, createdTime=Fri Dec 09 07:24:07 CST 2022, time=2022-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1754049, encodeId=db511e54049dc, content=<a href='/topic/show?id=dd6f2849351' target=_blank style='color:#2F92EE;'>#儿童过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28493, encryptionId=dd6f2849351, topicName=儿童过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aff136654610, createdName=charl1234579, createdTime=Tue Dec 06 01:24:07 CST 2022, time=2022-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1192064, encodeId=12261192064af, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=184a5613511, createdName=ms5000000018187740, createdTime=Thu Feb 10 22:03:51 CST 2022, time=2022-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329589, encodeId=a0891329589c3, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon Jan 17 12:24:07 CST 2022, time=2022-01-17, status=1, ipAttribution=)]
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    2022-02-10 ms5000000018187740

    学习了

    0

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    2022-01-17 膀胱癌

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