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Lancet Infect Dis：人T淋巴细胞白血病1型病毒感染相关疾病研究

2019-10-22 MedSci MedSci原创

人T淋巴细胞白血病1型病毒HTLV-1
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研究证实多种疾病与HTLV-1感染相关

人T淋巴细胞白血病1型病毒 (HTLV-1)是一种引起终生感染的人逆转录病毒，包括一种侵袭性的白血病，被认为与HTLV-1有关。除了已知的疾病，HTLV-1对健康的其他影响还存在不确定性。近日研究人员考察了综合流行病学研究中有关健康结果与HTLV-1之间关系。

本次研究为系统综述及荟萃分析，收集截至2018年7月的相关资料，包括队列、病例对照和对照的横断面研究。

39项研究符合纳入标准，检查了其中42项临床条件。与HTLV-1阴性者相比，HTLV-1患者全因死亡风险较高(RR：1.57)。荟萃分析显示，HTLV-1与脂溢性皮炎(OR：3.95)、干燥综合征（3.25）风险相关，而与胃癌相对风险(RR：0.45)呈负相关。从单项研究来看，还有16种与HTLV-1有关，包括儿童湿疹、支气管扩张症、支气管炎、毛细支气管炎、男性哮喘、纤维肌痛、类风湿关节炎、关节炎、肺结核、肾和膀胱感染、皮肤癣菌病、社区获得性肺炎、强螺旋体过度感染综合征、肝癌、成人T细胞白血病-淋巴瘤以外的淋巴瘤以及宫颈癌。

研究证实多种疾病与HTLV-1感染相关。

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    2020-06-06 kord1982

    #T淋巴细胞白血病#

    0

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    2020-02-14 amy0550

    #疾病研究#

    0

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    2020-06-15 sunyl07

    #淋巴细胞白血病#

    0

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    2020-07-26 cmj8wellington

    #Dis#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1967938, encodeId=d819196e938b6, content=<a href='/topic/show?id=6e301800534' target=_blank style='color:#2F92EE;'>#T淋巴细胞白血病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18005, encryptionId=6e301800534, topicName=T淋巴细胞白血病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Jun 06 01:34:00 CST 2020, time=2020-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2070438, encodeId=fd1020e043804, content=<a href='/topic/show?id=f30de0713e1' target=_blank style='color:#2F92EE;'>#疾病研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70713, encryptionId=f30de0713e1, topicName=疾病研究)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=010d202, createdName=amy0550, createdTime=Fri Feb 14 22:34:00 CST 2020, time=2020-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997959, encodeId=7f81199e959d2, content=<a href='/topic/show?id=75ff66001cd' target=_blank style='color:#2F92EE;'>#淋巴细胞白血病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66001, encryptionId=75ff66001cd, topicName=淋巴细胞白血病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Mon Jun 15 00:34:00 CST 2020, time=2020-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013091, encodeId=a0eb201309166, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Jul 26 17:34:00 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830300, encodeId=86c7183030034, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Jul 10 10:34:00 CST 2020, time=2020-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1302272, encodeId=0a5b13022e213, content=<a href='/topic/show?id=82a6659902c' target=_blank style='color:#2F92EE;'>#淋巴细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65990, encryptionId=82a6659902c, topicName=淋巴细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e34303, createdName=wetgdt, createdTime=Thu Oct 24 09:34:00 CST 2019, time=2019-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602909, encodeId=1678160290957, content=<a href='/topic/show?id=e0ee180038f' target=_blank style='color:#2F92EE;'>#T淋巴细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18003, encryptionId=e0ee180038f, topicName=T淋巴细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af0c18977520, createdName=zhenjiu129, createdTime=Thu Oct 24 09:34:00 CST 2019, time=2019-10-24, status=1, ipAttribution=)]
    2020-07-10 howi

    #Lancet#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1967938, encodeId=d819196e938b6, content=<a href='/topic/show?id=6e301800534' target=_blank style='color:#2F92EE;'>#T淋巴细胞白血病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18005, encryptionId=6e301800534, topicName=T淋巴细胞白血病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Jun 06 01:34:00 CST 2020, time=2020-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2070438, encodeId=fd1020e043804, content=<a href='/topic/show?id=f30de0713e1' target=_blank style='color:#2F92EE;'>#疾病研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70713, encryptionId=f30de0713e1, topicName=疾病研究)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=010d202, createdName=amy0550, createdTime=Fri Feb 14 22:34:00 CST 2020, time=2020-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997959, encodeId=7f81199e959d2, content=<a href='/topic/show?id=75ff66001cd' target=_blank style='color:#2F92EE;'>#淋巴细胞白血病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66001, encryptionId=75ff66001cd, topicName=淋巴细胞白血病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Mon Jun 15 00:34:00 CST 2020, time=2020-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013091, encodeId=a0eb201309166, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sun Jul 26 17:34:00 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1830300, encodeId=86c7183030034, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Jul 10 10:34:00 CST 2020, time=2020-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1302272, encodeId=0a5b13022e213, content=<a href='/topic/show?id=82a6659902c' target=_blank style='color:#2F92EE;'>#淋巴细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65990, encryptionId=82a6659902c, topicName=淋巴细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e34303, createdName=wetgdt, createdTime=Thu Oct 24 09:34:00 CST 2019, time=2019-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602909, encodeId=1678160290957, content=<a href='/topic/show?id=e0ee180038f' target=_blank style='color:#2F92EE;'>#T淋巴细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18003, encryptionId=e0ee180038f, topicName=T淋巴细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af0c18977520, createdName=zhenjiu129, createdTime=Thu Oct 24 09:34:00 CST 2019, time=2019-10-24, status=1, ipAttribution=)]
    2019-10-24 wetgdt

    #淋巴细胞#

    0

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    2019-10-24 zhenjiu129

    #T淋巴细胞#

    0