JACC:对于高血压前期或1级高血压,低盐+饮食干预比降压药还管用

2017-11-28 卢芳 中国循环杂志

好好吃饭比吃降压药还顶用?

好好吃饭比吃降压药还顶用?

近期一项发表于JACC上的研究确实显示,对于高血压前期或1级高血压患者,低盐+饮食干预的降压效应堪比吃药,甚至比降压药还管用。

长期被美国心脏协会所推荐的饮食叫DASH饮食,主要包括丰富的果蔬、全麦、以及低脂或无脂乳制品、鱼类、家禽、豆类、坚果种子类等。

研究者指出,这一研究结果提示,对于高危或1级高血压患者,饮食干预应该纳入常规一线治疗。

在这项研究中,研究者共纳入23-76岁的412位受试者,这些受试者收缩压在120-159 mmHg,舒张压在80-95 mmHg。

在研究伊始,这些受试者均没有应用任何降压药或胰岛素,之前也无心脏病、肾功能不全、血脂控制不理想或糖尿病等病史。

受试者首先随机给予12周的DASH饮食和对照饮食,对照饮食为美国人正常饮食。所有受试者在4周内随机给予不同含钠盐量:低(50 mmol/d)、中(100 mmol/d)、高(150 mmol/d)。100 mmol/d钠相当于2.3 g钠盐。

受试者根据基线收缩压分为4组:120-129mmHg,130-139 mmHg,140-149 mmHg和≥150 mmHg。

4周后,研究者发现,≥150mmHg的患者组,仅食用DASH饮食,其收缩压就平均下降了11mmHg;基线收缩压不到130 mmHg者,采用DASH饮食,收缩压下降了4 mmHg。

较之高盐对照饮食组,低盐+DASH饮食,可使基线收缩压不到130 mmHg者收缩压下降了5 mmHg;使130-139 mmHg组,收缩压下降了7 mmHg;140-149 mmHg组收缩压下降了10 mmHg。

最为惊奇的是≥150 mmHg的患者组,低盐+DASH饮食使其收缩压下降了21 mmHg。

要知道FDA要求任何降压药物要想批准,其收缩压必须降低3-4 mmHg。目前市场上很多降压药物,比如ACEI、β受体阻滞剂或钙拮抗剂,平均可使收缩压降低10-15 mmHg。

不过研究者指出,该研究未纳入收缩压在160 mmHg者以及有心血管病史和应用降糖药物的糖尿病患者,未来可针对这些人群来进一步明确低盐+DASH的“威力”。

原始出处:
Juraschek SP, Miller ER 3rd, Weaver CM,et al. Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure. J Am Coll Cardiol. 2017 Nov 4.

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    2018-07-31 hbwxf
  2. 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    2017-12-06 虈亣靌

    不错的文章值得推荐

    0

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    2017-12-01 2401

    做到低盐饮食在中国的饮食文化背景下.感觉很难.但通过饮食控制血压确实比药物要来得好.对了.DASH饮食是指什么饮食.其成本在我国是怎样的?

    0

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    2017-12-01 jihuaijun1112

    学习学习学习

    0

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    2017-11-30 虈亣靌

    学习了谢谢作者分享!

    0

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