Circulation:乳腺癌筛查也能顺便预测心脏病!美研究称:乳腺动脉钙化提示心脏病风险高

2020-01-11 xujing 中国循环杂志

美国研究者发现,利用这一项已经被广泛应用的检查,在不增加额外的费用或辐射暴露情况下,或许可以筛查心脏病高危人群。

通过乳房X光检查进行乳腺癌筛查,可以挽救数十万人的生命。通常建议女性从40或50岁开始,每年或两年进行一次乳房X光检查。

美国研究者发现,利用这一项已经被广泛应用的检查,在不增加额外的费用或辐射暴露情况下,或许可以筛查心脏病高危人群。

除了显示肿块外,数字乳腺摄影还可以显示乳腺动脉钙化情况。

据估计,大约13%的女性有乳腺动脉钙化,其中40多岁的女性约占10%,80多岁的女性约占一半。

早期的研究发现,乳腺动脉钙化的存在预示着心脏病发作、中风和其他心血管病风险增加。

而且有研究提示乳腺动脉中钙的积累和冠状动脉钙化有关。

这项研究分析了2006-2016年278名中老年女性的检查记录,她们在一年的时间内同时接受了乳房X光检查和冠状动脉钙化检查。

研究发现,几乎三分之一的女性患有乳腺动脉钙化,7%患有心力衰竭。

校正了年龄、糖尿病高血压等所有的心力衰竭危险因素后,乳腺动脉钙化女性发生心力衰竭或心力衰竭进展的风险增加2.2倍。

研究者称,乳腺动脉钙化可能是血管僵硬和内皮功能障碍的早期标志物,采用乳腺动脉钙化可以识别出心衰的高危人群。

原始出处:Quan M Bui, Avinash Toomu, Paula Anzenberg, et al. Abstract 11552: Breast Arterial Calcification and Risk of Heart Failure. Circulation. 2019,140:A11552.

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    2020-01-14 一天没事干

    很好的学习机会

    0

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    2020-01-12 飛歌

    学习了很有用不错

    0

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    2020-01-11 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

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由此可见,AI系统的强大评估能力为临床试验铺平了道路,以提高乳腺癌筛查的准确性和效率。

王碧芸:2019年HER2+乳腺癌进展盘点

进展1 CLEOPATRA研究 CLEOPATRA研究是一项Ⅲ期、随机、双盲、安慰剂对照研究,入组808例HER2阳性晚期转移性乳腺癌(MBC)患者,旨在比较一线曲妥珠单抗联合化疗基础上,增加帕妥珠单抗是否能够进一步改善HER2阳性晚期乳腺癌患者的预后,以及三药联合治疗的安全性。 该研究首次证明在曲妥珠单抗联合化疗基础上增加帕妥珠单抗能够改善HER2阳性晚期乳腺癌的无进展生存和总生存

Sci Rep:降压药与丙戊酸联合逆转乳腺癌进展!

导 语:2017年,美国乔治城大学的一项研究发现,高脂饮食会改变雌性小鼠基因的表达,进而增加雌性后代患乳腺癌的风险。而且这种影响可以波及到后面的三代雌性。一石激起千层浪,在优生优育的当今,该研究给诸多正在备孕或者已经怀孕的孕妈发出了警告,毕竟,饮食与癌症之间的关系确实已有流行病学研究进行过佐证。