BMC Gastroenterology: 越胖的人越容易得便秘!

2021-05-16 MedSci原创 MedSci原创

便秘是一个影响着全世界范围内许多人的现实问题,尤其是老年人,便秘的问题相当普遍。

      便秘是一个影响着全世界范围内许多人的现实问题,尤其是老年人,便秘的问题相当普遍。在全球范围内,成人便秘的发生率约为16%,一些研究已经确定了普通人群中发生便秘的危险因素:女性,高龄,社会地位较低,缺乏运动,糖尿病,药物治疗和饮食因素,例如低纤维消耗,低液体摄入和高消耗快餐等。另外,妇女中激素的使用紊乱和肥胖症均与便秘有关。肥胖是一种多因素造成的慢性疾病,其特征的身体脂肪过度积累和,当BMI大于35Kg/m2时被定义为III级肥胖,小于35Kg/m2时被认为是II级肥胖。1974年至2014年间,研究人员对200多个国家的BMI趋势进行了研究,结果显示,全球II级和III级肥胖症的患病率在男性中为2.3%,在女性中为5.0%。虽然便秘是肥胖是常见的危险因素。然而,对于严重肥胖者及其相关因素中便秘的发生知之甚少。因此,本项研究旨在对过于肥胖的患者进行相关研究,评估II级和III级肥胖患者的肠道便秘及其相关因素的患病率。

 

      研究人员收集并分析了居住在巴西戈亚尼亚大都会地区的年龄在18-64岁间的体重指数(BMI)≥35 kg/m2的成年人的随机临床试验的基线数据。使用包含社会人口统计学,生活方式,肥胖程度,合并症,饮水量和食物消耗变量的调查表收集相关数据。主要观察结局是由罗马III标准的便秘情况。回归分析用于评估解释变量与结果之间的关联。

 

      研究结果显示在150名参与者中,便秘的患病率为24.67%(95%CI:17.69–31.64)。经过多元回归分析后,便秘与药物使用相关(PR:2.99、95%CI:1.18-7.57,p = 0.021),年龄较小的患者也更容易患便秘(即18-29岁)(PR:3.12、95%CI:1.21-8.06,p = 0.019)。以前吸烟(PR:3.24,95%CI:1.28-9.14,p = 0.014)与便秘的发生也有关系。便秘与每日摄入富含纤维的食物之间没有统计学上的显着相关性。

图:与便秘相关的危险因素

      本项研究发现在患有肥胖症的II级和III级成年人中,便秘的患病率很高。便秘与同时使用药物,年龄较小的人群以及曾经吸烟的人显着相关。因此,临床医生应该对这部分患者给予更多的关注。

 

 

原始出处:

Erika Aparecida Silveira. Et al.Prevalence of constipation in adults with obesity class II and III and associated factors.BMC Gastroenterology.2021.

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    2021-12-23 ms7000000460666888

    便秘和肥胖恶性循环

    0

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encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Oct 01 00:20:09 CST 2021, time=2021-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975084, encodeId=53e019e508413, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Mon Mar 14 06:20:09 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966911, encodeId=7e2c966911a0, content=赚积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38f35410495, createdName=ms9000001538930661, createdTime=Wed May 19 15:31:14 CST 2021, time=2021-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1505252, encodeId=bffb1505252f1, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue May 18 10:20:09 CST 2021, time=2021-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966250, encodeId=0ee196625058, content=瘦点好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd5b5469613, createdName=ms6000001624652641, createdTime=Sun May 16 21:08:50 CST 2021, time=2021-05-16, status=1, ipAttribution=)]
    2021-10-01 许安
  5. 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encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Oct 01 00:20:09 CST 2021, time=2021-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975084, encodeId=53e019e508413, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Mon Mar 14 06:20:09 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966911, encodeId=7e2c966911a0, content=赚积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38f35410495, createdName=ms9000001538930661, createdTime=Wed May 19 15:31:14 CST 2021, time=2021-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1505252, encodeId=bffb1505252f1, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue May 18 10:20:09 CST 2021, time=2021-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966250, encodeId=0ee196625058, content=瘦点好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd5b5469613, createdName=ms6000001624652641, createdTime=Sun May 16 21:08:50 CST 2021, time=2021-05-16, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2065353, encodeId=ead5206535352, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Thu Jun 17 13:20:09 CST 2021, time=2021-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712804, encodeId=a4eb1e128047e, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Oct 01 00:20:09 CST 2021, time=2021-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975084, encodeId=53e019e508413, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Mon Mar 14 06:20:09 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966911, encodeId=7e2c966911a0, content=赚积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38f35410495, createdName=ms9000001538930661, createdTime=Wed May 19 15:31:14 CST 2021, time=2021-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1505252, encodeId=bffb1505252f1, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue May 18 10:20:09 CST 2021, time=2021-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966250, encodeId=0ee196625058, content=瘦点好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd5b5469613, createdName=ms6000001624652641, createdTime=Sun May 16 21:08:50 CST 2021, time=2021-05-16, status=1, ipAttribution=)]
    2021-05-19 ms9000001538930661

    赚积分

    0

  7. 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encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Oct 01 00:20:09 CST 2021, time=2021-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975084, encodeId=53e019e508413, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Mon Mar 14 06:20:09 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966911, encodeId=7e2c966911a0, content=赚积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38f35410495, createdName=ms9000001538930661, createdTime=Wed May 19 15:31:14 CST 2021, time=2021-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1505252, encodeId=bffb1505252f1, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue May 18 10:20:09 CST 2021, time=2021-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966250, encodeId=0ee196625058, content=瘦点好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd5b5469613, createdName=ms6000001624652641, createdTime=Sun May 16 21:08:50 CST 2021, time=2021-05-16, status=1, ipAttribution=)]
  8. 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channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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    2021-05-17 ms2000001361349190

    瘦点好

    0

  9. 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channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd5b5469613, createdName=ms6000001624652641, createdTime=Sun May 16 21:08:50 CST 2021, time=2021-05-16, status=1, ipAttribution=)]
    2021-05-16 1475e534m59暂无昵称

    减肥有利健康

    0

  10. 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channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Mon May 17 13:21:06 CST 2021, time=2021-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966091, encodeId=49b99660912a, content=减肥有利健康, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85e85211318, createdName=1475e534m59暂无昵称, createdTime=Sun May 16 21:12:49 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=966088, encodeId=5af696608875, content=要减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd5b5469613, createdName=ms6000001624652641, createdTime=Sun May 16 21:08:50 CST 2021, time=2021-05-16, status=1, ipAttribution=)]
    2021-05-16 ms6000001624652641

    要减肥

    0

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