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Orchard筹集1.5亿美元推进基因治疗

2018-08-14 MedSci MedSci原创

Orchard1.5亿美元基因治疗
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英国生物技术公司Orchard Therapeutics已筹集1.5亿美元推进其基因治疗管线。

英国生物技术公司Orchard Therapeutics已筹集1.5亿美元推进其基因治疗管线。

该公司表示将利用这笔资金推进三项临床项目：OTL-101治疗腺苷脱氨酶严重联合免疫缺陷，OTL-200治疗异染性脑白质营养不良，和OTL-103治疗Wiskott-Aldrich综合征（WAS）。同时还将用于支持Orchard罕见疾病基因治疗管道的临床和临床前开发。

Orchard总裁兼首席执行官马克·罗瑟拉说："我们很高兴能够在这次融资中获得新老投资者的大力支持。"

该公司首席财务和首席商务官Frank Thomas补充道："这项融资为Orchard提供了额外资金，以便将我们最先进的临床计划迅速推向商业化。我们正在推进初级免疫缺陷和神经代谢紊乱方面的基因疗法的管道，希望能尽快用于治疗患者。"

早在4月份，Orchard公司成功抢购全球制药巨头葛兰素史克公司（GSK）开发的罕见病基因疗法，交易后GSK将成为Orchard的投资者，坐拥19.9%的股权以及公司董事会席位。

Orchard收购的项目包括Strimvelis，这是2016年欧盟批准的第一个针对腺苷脱氨酶严重联合免疫缺陷症（ADA-SCID）儿童的离体自体基因疗法，以及两项正在进行的异染性脑白质营养不良的晚期临床项目和威斯科特奥尔德里奇综合征，和一种用于β地中海贫血的临床计划。在完成1型粘多糖病（MPS1或Hurler综合征），慢性肉芽肿性疾病和球状细胞脑白质营养不良的临床证据收集后，Orchard还将获得独家授权GSK合作伙伴Telethon / Ospedale San Raffaele的三项额外临床前计划。这些计划都将补充Orchard公司的临床和临床前基因疗法。

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    2018-08-15 1e145228m78(暂无匿称)

    学习了，谢谢作者分享!

    0

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    2018-08-14 天地飞扬

    了解一下，谢谢分享！

    0

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    2018-08-14 清风拂面

    谢谢分享学习

    0

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    2018-08-14 惠映实验室

    学习了，谢谢分享。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=338789, encodeId=3a88338e893f, content=学习了，谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Wed Aug 15 16:58:18 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338624, encodeId=850a3386249a, content=了解一下，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Tue Aug 14 23:21:04 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338606, encodeId=c81e33860604, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Aug 14 22:41:01 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338595, encodeId=867533859596, content=学习了，谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue Aug 14 22:06:25 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338588, encodeId=a5d93385885e, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Tue Aug 14 21:37:40 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338584, encodeId=ab6a338584b2, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Tue Aug 14 21:13:36 CST 2018, time=2018-08-14, status=1, ipAttribution=)]
    2018-08-14 一天没事干

    很好的学习机会

    0

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    2018-08-14 wqkm

    ^_^^_^^_^

    0