Int J Pediatr Otorhin:儿童扁桃体切除术后心动过缓是否与术中右美托咪定的使用有关?

2018-03-04 王贵龙 “罂粟花”微信号

儿童扁桃体切除术心动过缓与术中右美托咪定使用无直接关系,心动过缓的发生可能受心肺功能监测技术的影响。

背景与目的

右美托咪定作为一种新型药物,其在伴睡眠呼吸暂停综合征(OSA)的患儿扁桃体切除术中常作为辅助用药。尽管右美托咪定安全有效,但其中枢交感神经阻断效应引起的低血压与心动过缓等副作用不容忽视。出于安全考虑,本团队对扁桃体切术后OSA患儿进行夜间心肺功能监测,在监测过程中,我们不少发现心动过缓的患儿,因此本研究拟探讨扁桃体切除术后OSA患儿行动过缓是否与术中右美托咪定使用有关。

方  法

本实验为回顾性队列研究,我们回顾性分析了11个月内的记录,比较了接受右美托咪定和未接受右美托咪定的扁桃体切除术后患儿心动过缓的发生率。

结  果

本队列研究共纳入921例患儿,术中接受右美托咪定的共371例,未接受右美托咪定的共550例;心动过缓总发生率为7.2%(66例患儿);所有患儿心动过缓及临床表现均不需要医护措施干预,两组间心动过缓发生率无明显差异。

结  论

本研究结果表明:儿童扁桃体切除术心动过缓与术中右美托咪定使用无直接关系,心动过缓的发生可能受心肺功能监测技术的影响。

原始出处:

Bush B, Tobias J D, Lin C, et al. Postoperative bradycardia following adenotonsillectomy in children: Does intraoperative administration of dexmedetomidine play a role?[J]. Int J Pediatr Otorhinolaryngol, 2018, 104:210-215.

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    2018-08-05 feather89
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1638463, encodeId=0c8b163846315, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Mon Jun 04 08:31:00 CST 2018, time=2018-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1722319, encodeId=86ee1e2231943, content=<a href='/topic/show?id=b9d95429465' target=_blank style='color:#2F92EE;'>#扁桃体切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54294, encryptionId=b9d95429465, topicName=扁桃体切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d2d33261552, createdName=xzw124, createdTime=Tue Jun 19 04:31:00 CST 2018, time=2018-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004881, encodeId=6d702004881ee, content=<a href='/topic/show?id=ed4854296bb' target=_blank style='color:#2F92EE;'>#扁桃体切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54296, encryptionId=ed4854296bb, topicName=扁桃体切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fd18451, createdName=xre2008, createdTime=Wed Jul 11 16:31:00 CST 2018, time=2018-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727116, encodeId=f05c1e2711691, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Aug 05 21:31:00 CST 2018, time=2018-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1877000, encodeId=affa18e700077, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Thu Jun 07 23:31:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295141, encodeId=02c529514131, content=不错.学习了.谢谢分享.好好总结反思, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/17/cfa76f1048392033b44c71e9bcb628d9.jpg, createdBy=096c2156900, createdName=梦想起航ing, createdTime=Sun Mar 11 09:07:35 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293414, encodeId=1bb42934149f, content=学习了.好文章., beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Mar 06 06:10:48 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554140, encodeId=87b6155414012, content=<a href='/topic/show?id=33c950903aa' target=_blank style='color:#2F92EE;'>#心动过缓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50903, encryptionId=33c950903aa, topicName=心动过缓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=424914510212, createdName=xuqianhua, createdTime=Tue Mar 06 01:31:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292903, encodeId=d5a6292903b8, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun Mar 04 11:00:13 CST 2018, time=2018-03-04, status=1, ipAttribution=)]
    2018-03-11 梦想起航ing

    不错.学习了.谢谢分享.好好总结反思

    0

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    2018-03-06 1e0f8808m18(暂无匿称)

    学习了.好文章.

    0

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    2018-03-04 wqkm

    ^_^^_^^_^

    0

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