DIABETOLOGIA:2型糖尿病与突发听力损失的风险如何?

2019-04-06 不详 网络

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2糖尿病被认为是听力下降的危险因素,它涉及的可能的机制包括微血管疾病、听神经病变或氧化应激。一些小型研究已经检验了2糖尿病和听力损失之间的纵向联系,但还需要更大规模的研究。我们的目的是研究2糖尿病(包括糖尿病持续时间)是否与突发听力损失相关。

研究人员对139909名女性进行了一项纵向研究,以检验2型糖尿病与自我报告的听力损失风险之间的关系。从两年一次的问卷调查中确定了糖尿病的医生诊断。主要结果是,在2012NHS I2009年或2013NHS II的问卷调查中,听力损失的严重程度报告为中度或更严重(分为“中度或重度”听力问题,或“中度听力障碍或聋子”)Cox比例危险回归被用来调整潜在的混杂因素。

结果显示,在240万人年的随访中,2型糖尿病患者中有664例出现中度或更严重的听力损失,而非2型糖尿病患者中有1022例听力损失。与没有患2型糖尿病的女性相比,患2型糖尿病的女性发生中度或更严重听力损失的风险更高(合并多变量校正的HR 1.16 [95% CI 1.07, 1.27])。与非2型糖尿病患者相比,患有2型糖尿病≥8年的患者中度或更严重听力损失的风险更高(合并多变量调整HR 1.24 [95% CI 1.10, 1.40])

在这项大型的纵向研究中,2型糖尿病与中度或更严重听力损失的风险相对较高。此外,糖尿病持续时间越长,中度或更严重听力损失的风险就越大。

原始出处:

Shruti GuptaRoland D. EaveyMolin WangType 2 diabetes and the risk of incident hearing loss

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    2019-04-08 ysjykql
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    2019-04-07 misszhang

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