ESC 2014:降血压可使2型糖尿病者长期获益(ADVANCE-ON研究)

2014-09-09 CMT 中国医学论坛报今日循环

John P Charlmers 教授 澳大利亚研究人员发现,2型糖尿病患者在接受降压治疗后的数年内,心脏病发病率和死亡率均有下降。在停用培哚普利吲达帕胺降压复方制剂6年后,2型糖尿病患者的心脏病发病率和死亡率仍处于低水平。 这项名为ADVANCE-ON的研究在20个国家中进行,对ADVANCE试验(n=11000)中超过80%的受试者进行随访。 在ADVANCE研究

ADVANCE-ON研究

John P Charlmers 教授

澳大利亚研究人员发现,2型糖尿病患者在接受降压治疗后的数年内,心脏病发病率和死亡率均有下降。在停用培哚普利吲达帕胺降压复方制剂6年后,2型糖尿病患者的心脏病发病率和死亡率仍处于低水平。

这项名为ADVANCE-ON的研究在20个国家中进行,对ADVANCE试验(n=11000)中超过80%的受试者进行随访。

在ADVANCE研究中,研究人员发现,使用血管紧张素转换酶抑制剂(ACEI)和利尿剂降压将近5年的患者,其心脏病发病和死亡风险都有所降低。在ADVANCE-ON随访研究中发现,这种获益在6年后仍然存在,只是与强化治疗期间相比有所降低。

研究主要负责人(PI),乔治全球健康研究院及悉尼大学John Chalmers教授在欧洲心血管病学会(ESC)年会上介绍,“研究强调了针对2型糖尿病患者积极降压治疗的重要性。好消息是,治疗为患者带来益处的持续时间比治疗本身的时间更长。而更重要的是,为了挽救更多生命,积极降压治疗无论从短期还是长期来说都是必需的。”

研究主管Sophia Zoungas教授补充道,“尽管既往有研究在高血压患者中发现类似结果,但这对2型糖尿病患者来说是一个全新的发现。”


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    2015-04-11 x35042875

    控制好糖尿病可能提高肝硬化患者的预后。

    0

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    2014-09-09 sweetai

    很好,非常有帮助!

    0

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