AHJ:功能性电刺激可改善HFpEF患者生活质量

2013-09-22 高晓方 译 医学论坛网

希腊一项研究表明,功能性电刺激(FES)可改善左室射血分数正常心衰(HFpEF)患者的运动能力、生活质量、情绪状况和内皮功能。论文9月3日在线发表于《美国心脏杂志》(Am Heart J)。【原文阅读】 此项研究共纳入30例HFpEF患者,并按1:1比率随机给予6周FES治疗或安慰治疗。受试者平均年龄69 ± 8岁,NYHA分类为II或III,平均

希腊一项研究表明,功能性电刺激(FES)可改善左室射血分数正常心衰(HFpEF)患者的运动能力、生活质量、情绪状况和内皮功能。论文9月3日在线发表于《美国心脏杂志》(Am Heart J)。【原文阅读】

此项研究共纳入30例HFpEF患者,并按1:1比率随机给予6周FES治疗或安慰治疗。受试者平均年龄69 ± 8岁,NYHA分类为II或III,平均射血分数为63 ± 6%。在基线和治疗完成后对6分钟步行距离、生活质量、抑郁症状、B型利钠肽、内皮功能和左室舒张功能进行评估。

结果显示,与安慰治疗相比,FES组受试者的6分钟步行距离(P=0.001)、堪萨斯城心肌病问卷评分(P=0.006)、明尼苏达生活质量调查表评分(P=0.017)、贝克抑郁问卷评分(P=0.015)、Zung抑郁量表评分(P=0.019)和内皮功能(P=0.002)均出现显著改善,B型利钠肽出现非显著性降低,并且二尖瓣E/e’比呈降低趋势(P=0.091)。

原文阅读

Apostolos Karavidas.Metaxia Driva.John T Parissis.Dimitrios Farmakis.Vassiliki Mantzaraki .Christos Varounis.Ioannis Paraskevaidis.Ignatios Ikonomidis . Vlassios Pirgakis. Maria Anastasiou-Nana.Gerasimos Filippatos . Functional electrical stimulation of peripheral muscles improves endothelial function and clinical and emotional status in heart failure patients with preserved left ventricular ejection fraction .AHJ 03 September 2013.


    

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    2013-12-17 feather89
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    2013-09-24 bettycmoon
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