Heart:抗炎饮食与腹主动脉瘤风险

2019-07-13 xing.T MedSci原创

由此可见,坚持高抗炎潜力饮食与降低AAA风险相关,这种关联对于AAA破裂更为明显。

饮食模式与腹主动脉瘤(AAA)发生发展之间的关系尚不清楚。近日,心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员前瞻性地评估了饮食的抗炎潜力与AAA风险之间的关联。 

研究人群包括瑞典男性队列(45072名男性)和瑞典乳房影像学队列(36633名女性),年龄为45-83岁。研究人员使用抗炎饮食指数(AIDI)估算饮食的抗炎潜力,该指数基于11种具有抗炎潜力的食物和5种具有促炎潜力的食物(最高16分),其针对高敏感性C反应蛋白(hsCRP)进行了验证。Cox比例风险回归模型用于估计HR和95%CI。在14.9年的随访期间(1217263人次每年),通过瑞典住院登记中心、全国死因登记中心和血管外科登记中心(Swedvasc)确定了1528例AAA病例(277例(18%)破裂,1251例未破裂)。

研究人员观察到女性和男性的AIDI与AAA风险呈负相关;AIDI的极端四分位数(≥8 vs. ≤5分)之间的HR在女性中为0.55(95%CI为0.36至0.83),男性为0.81(95%CI为0.68至0.98)。AIDI与破裂和未破裂的AAA发病率呈负相关;AIDI最高四分位数参与者与最低四分位数的参与者相比,AAA破裂的HR为0.61(95%CI为0.41-0.90),非破裂AAA的HR为0.79(95%CI为0.65-0.95)。 

由此可见,坚持高抗炎潜力饮食与降低AAA风险相关,这种关联对于AAA破裂更为明显。 

原始出处:

Joanna Kaluza.et al.Anti-inflammatory diet and risk of abdominal aortic aneurysm in two Swedish cohorts.Heart.2019.http://dx.doi.org/10.1136/heartjnl-2019-315031

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