Eur Radiol:诊断胰腺癌就单单开个磁共振检查单?磁共振弹性成像在诊断胰腺癌中价值!

2017-10-31 shaosai MedSci原创

胰腺导管腺癌是常见的一种胰腺癌的类型,它可以分为4期。一期无残留的肿瘤切除生存时间要大大长于其他时期的导管腺癌,因此做好尽早的发现导管腺癌,对患者有着重要的意义。另外人们又常常不能够尽早的发现导管腺癌,能施行一期无肿瘤残存的手术人数只有5%。所以提高导管腺癌的诊断机制对导管腺癌的治愈有着重要的意义。本研究旨在验证MR弹性成像(MRE)并将其与血清CA19-9在鉴别良恶性胰腺肿块的诊断价值,尤其是胰

胰腺导管腺癌是常见的一种胰腺癌的类型,它可以分为4期。一期无残留的肿瘤切除生存时间要大大长于其他时期的导管腺癌,因此做好尽早的发现导管腺癌,对患者有着重要的意义。另外人们又常常不能够尽早的发现导管腺癌,能施行一期无肿瘤残存的手术人数只有5%。所以提高导管腺癌的诊断机制对导管腺癌的治愈有着重要的意义。本研究旨在验证MR弹性成像(MRE)并将其与血清CA19-9在鉴别良恶性胰腺肿块的诊断价值,尤其是胰腺导管内腺癌(PDAC)和肿块型胰腺炎(MFP),并将结果发表在Eur Radiol上。

本研究共纳入了85例经组织病理学检查证实的实性胰腺肿块的患者。评价肿块硬度计硬度比(以肿块硬度/胰腺硬度计算所得)。利用ROC曲线下面积(AUROC)分析诊断准确度。

最终诊断包括54例恶性肿瘤(43例PDAC患者)和31例良性肿块(24例MFP患者)。在鉴别良恶性胰腺肿瘤时,肿块硬度比的诊断价值要高于肿块硬度和血浆CA19-9(AUC: 0.912 vs. 0.845 vs. 0.702; P = 0.026, P < 0.001),尤其是在PDAC和MFP中(AUC: 0.955 vs. 0.882 vs. 0.745; P = 0.026, P = 0.003)。肿块硬度比鉴别PDAC和MFP的敏感性、特异性和准确性均高于0.9。

本研究表明,基于PDAC和MFP各自的机制特征,MRE在鉴别两种病变中具有高效并能够定量分析的价值。

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    2017-11-03 zb1235672

    好知识.值得学习!

    0

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    2017-10-31 1e1b8538m79(暂无匿称)

    不错的文章值得一读

    0

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    2017-10-31 1e1a50a1m36(暂无匿称)

    谢谢分享知识

    0

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