Clinical Nutrition: 饮食对老年痴呆症风险的影响

2021-07-03 MedSci原创 MedSci原创

长寿是我们所有人想要的,但长寿也带有与年龄相关的慢性疾病的副作用,比如年纪大了以后出现痴呆症是最严重和最普遍的疾病之一,痴呆症缺乏有效的治疗方法。

      长寿是我们所有人想要的,但长寿也带有与年龄相关的慢性疾病的副作用,比如年纪大了以后出现痴呆症是最严重和最普遍的疾病之一。由于痴呆症缺乏有效的治疗方法,因此非常需要预防或延迟它的出现。饮食习惯和营养已被发现是许多慢性病的重要可改变风险因素,但饮食对痴呆风险作用的证据仍然有限,尤其是在高龄人群中这样的研究更少。本项研究旨在探究地中海饮食及其成分与老年人普遍和偶发性痴呆的关系。

 

      意大利瓦雷泽省对 80 岁或 80 岁以人群的进行相关研究。使用经过验证的食物频率问卷来收集上一年消费的 23 种不同食物的信息,然后研究人员计算地中海饮食评分并将其成分为高中低三组。痴呆患病率和发病率的多变量模型根据人口统计学和临床特征进行了调整。

 

      本项横断面研究中共纳入1390 名受试者,平均年龄分别为 93 岁和 92 岁。坚持地中海饮食,更多地食用鸡蛋、水果和蔬菜、碳水化合物和更多的食物摄入量与较低的痴呆症患病率相关。在 2.8 年的平均随访期间,每周增加豆类摄入量显着降低了痴呆症的发病率:最高与最低三分位数(95% 置信区间)的相应风险比为 0.66 (0.46–0.95) 。

图:地中海饮食模式

       本项研究发现在痴呆症患者中,最年长的老人吃得更少,饮食种类和营养密度都较低。纵向分析证实,吃得更多的年龄最大的受试者以及豆类摄入量更高的受试者患痴呆症的风险降低。

 

 

原始出处:

Cristina Nicoli. Et al. The role of diet on the risk of dementia in the oldest old: The Monzino 80-plus population-based study. Clinical Nutrition.2021.

 

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    2022-02-06 Boyinsh
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    2021-07-05 zll0628
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    2021-07-04 春风得意225

    学习了

    0

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    2021-07-03 junJUN

    老年人痴呆何药可用??

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1661646, encodeId=876c16616465e, content=<a href='/topic/show?id=1b3c1315481' target=_blank style='color:#2F92EE;'>#nutrition#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13154, encryptionId=1b3c1315481, topicName=nutrition)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6f0d25331316, createdName=膀胱癌, createdTime=Fri May 27 16:35:33 CST 2022, time=2022-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836271, encodeId=f60c18362e15c, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Sun Feb 06 02:35:33 CST 2022, time=2022-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507763, encodeId=9a7a150e7636b, content=<a href='/topic/show?id=8764484014' target=_blank style='color:#2F92EE;'>#clinical#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4840, encryptionId=8764484014, topicName=clinical)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ee59933733, createdName=zll0628, createdTime=Mon Jul 05 05:35:33 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995959, encodeId=f863995959fc, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/D156E0EF49CCFB4A21015FB71B820F06/100, createdBy=7ba82197989, createdName=春风得意225, createdTime=Sun Jul 04 01:48:54 CST 2021, time=2021-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048827, encodeId=3727104882ec3, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Sat Jul 03 17:35:33 CST 2021, time=2021-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995771, encodeId=6ab4995e71a1, content=很不错,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/bb4c435996c647a69371bf55a2d576d1/48d68c18ad6043cf873582eef7e6c7f5.jpg, createdBy=1f402010073, createdName=如是我闻, createdTime=Sat Jul 03 16:32:28 CST 2021, time=2021-07-03, status=1, ipAttribution=)]
    2021-07-03 如是我闻

    很不错,学习了

    0

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