J Neuroophthalmol. :病例报告-重症肌无力患者的眼外肌研究揭示潜在眼肌麻痹症治疗方法!

2017-07-26 cuiguizhong MedSci原创

南非开普敦大学神经内科研究组的Rautenbach RM近日在最新的一期J Neuroophthalmol. 杂志上发表了一篇病例报告,他们首次指出:经过对眼麻痹症3.5年的临床治疗,对患有血清阴性重症肌无力(MG)患者的眼外肌(EOM)进行了组织病理学和超微结构组织分析。

南非开普敦大学神经内科研究组的Rautenbach RM近日在最新的一期J Neuroophthalmol. 杂志上发表了一篇病例报告,他们首次指出:经过对眼麻痹症3.5年的临床治疗,对患有血清阴性重症肌无力(MG)患者的眼外肌(EOM)进行了组织病理学和超微结构组织分析。

眼外肌(EOM)的主要是肌病症状,同时,超微结构发现线粒体功能紊乱,但最突出的特征是内皮胶原的增加和肌肉纤维中脂肪细胞的替换。对照组是来自斜视手术后的患者的眼外肌(EOM)。相比之下,两者具有相同的偏差持续时间,但对照组肌肉组织学诊断为正常。 虽然组织病理学和超微结构发现,大部分的眼外肌类似于重症肌无力(MG)中的肢体肌肉,但是丰富的肌内膜胶原在两者中不一样,可能是由于慢性眼肌麻痹导致的肌内膜胶原产生较少。这项工作帮助临床医生加深了对重症肌无力(MG)患者的眼外肌(EOM)的认识。

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    2017-07-27 130****4638

    学习了谢谢分享

    0

  8. 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    2017-07-27 执着追梦

    学习,谢谢分享

    0

  9. 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    2017-07-27 Y—xianghai

    学习了新知识

    0

  10. 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    2017-07-27 jihuaijun1112

    学习学习学习

    0