《都挺好》:苏大强的作妖史 就是一部阿尔兹海默症的发病史

2019-04-08 佚名 医界新闻汇

理解了苏大强,就理解了阿尔兹海默症。最近有一部叫做《都挺好》的电视剧非常火爆,几乎引起了海啸般的全民大讨论。这部剧的结尾,编剧使出了终极洗白大法——苏大强得了阿尔兹海默症!让一个不作不罢休的人变成了一个不记得儿女的可怜老人,同时也做了一些感人的事儿,最终迎来了大团圆的结局。作妖苏大强怎么说傻就傻了呢?不是编剧这剧情变得太快,而是苏大强这病,前面早就已经有铺垫了。有这6大征兆,警惕阿尔茨海默病!01

理解了苏大强,就理解了阿尔兹海默症。

最近有一部叫做《都挺好》的电视剧非常火爆,几乎引起了海啸般的全民大讨论。这部剧的结尾,编剧使出了终极洗白大法——苏大强得了阿尔兹海默症!让一个不作不罢休的人变成了一个不记得儿女的可怜老人,同时也做了一些感人的事儿,最终迎来了大团圆的结局。

作妖苏大强怎么说傻就傻了呢?不是编剧这剧情变得太快,而是苏大强这病,前面早就已经有铺垫了。

有这6大征兆,警惕阿尔茨海默病!

01 情绪或性格突然发生改变

与以前相比判若两人,只以自我为中心,不关心其他家里人,很自私、冷漠。开始变得糊涂、多疑、焦虑、抑郁,无缘无故地情绪涨落或暴躁易怒。

剧中苏大强在苏母去世后,性格突变,各种花式作妖。朱丽也在剧中曾经不止一次的说过,妈在世的时候爸不是这个样子的。这种状况或许也不全是长期压抑后的自我放飞,而是一种阿尔兹海默病的前兆

02 完成日常熟悉的任务有困难

忘记熟悉的游戏规则,忘记熟悉的日常操作,例如煮饭等。

剧中苏大强一大早起来煮粥,结果忘了关火造成煤气泄露引起厨房报警器大响,就是这种现象。苏明玉也说过以前苏母在世的时候,苏大强是会做饭的,但现在却要保姆陪护才能完成正常的日常生活。理解了这个征兆,就能明白他可能不是作,而是完成这些任务真的有困难。

03计划或解决问题困难

无法按照指示、解决问题和集中注意力,很难遵循规则或说明。

剧中苏大强经常混用朱丽的毛巾,还把马桶弄得一团糟。尽管苏明成多次给苏大强介绍过哪条是他的毛巾,但是苏大强还是经常搞混,就是这种前兆表现。

04判断力和理解力下降

在不必要的东西上花费太多(比如花200元买了个土豆,买房一定要买三室一厅);不注意个人仪容仪表,不定期洗澡或清洁。

剧中苏大强不爱洗澡,苏明成想打开窗子散散屋里的气味,苏大强一边挠痒一边阻止苏明成开窗。苏明成哄小孩似的劝苏大强去洗澡,苏大强却我行我素地拍上卧室门径直去睡觉了。这就是判断力和理解力下降的表现。

05 语言理解力下降

在交谈中跟不上他人的交谈思路,交谈时总是重复自己的话,词不达意,难以表达自己真实的想法。

剧中苏明成与朱丽闹离婚,苏明哲带苏大强去朱家道歉。苏明哲到朱家对朱丽父母说尽好话,朱父朱母态度终于松动。苏大强却仿佛没事人一般参观完朱家的装修,接话说朱丽就是娇生惯养,苏母生前就这么说过。越说越不在调,被忍无可忍的朱父朱母赶出家门。

在一些其他问题上,三个子女跟苏大强也很难沟通。这正是在交谈中跟不上他人的交谈思路的表现。

06 兴趣丧失

长时间地昏昏欲睡,无所事事;在电视机前呆坐好几个小时,却并没有真的在看什么节目;对以前的喜好不再有兴趣(比如以前喜欢买彩票,后来不买了)。

得阿尔兹海默症后,苏大强还能活多久

自1906年Alzheimer医生首次报告1例51岁女性病例以来,阿尔茨海默病(Alzheimer disease, AD)载入医学史册已110多年。

现在每3秒钟就有一位阿尔兹海默症患者产生,这是一个全球性的疾病。2018年,全球约有5000万人患有阿尔兹海默症,预计到2050年,这一数字将增至1.52亿,将是现在的三倍之多。

关于阿尔兹海默症患者的生存时间,以往国内外报道从病人出现症状开始的中位生存时间为5-9.3年,但Wolfson等研究结果显示,在校正长度偏差之后(不包括有快速进展性疾病且在纳入研究前就死亡的患者),阿尔兹海默症患者的中位生存时间减少了约50%,为3.33年。

阿尔兹海默症患者诊断后的生存时间较短,与人们对痴呆的认识程度较低,通常是在阿尔兹海默症病人出现行为症状,在家难于管理,或是出现躯体并发症时才将病人送至医院就医,此时病人已处于中、重度痴呆,生活不能自理,容易出现各种并发症,故诊断后的生存时间较短。

因此,如果能够早期识别阿尔兹海默症的征兆,尽早进行治疗和干预,或可延长阿尔兹海默症患者的生存时间。

参考资料:

1.Wolfson C, Wolfson DB, Asgharian M, et al. A reevaluation of the duration of survival after the onset of dementia [J]. N Engl J Med, 2001, 344(15):1111-1116.

2.20 early signs of Alzheimer’s disease https://www.msn.com/en-ph/health/wellness/20-early-signs-of-alzheimers-disease/ss-BBVpzs2

3.蒋亚斌. 阿尔茨海默病患者的生存时间和死亡原因[J]. 中国临床康复, 2002, 6(17):2558.

4.朱国旺. 十大征兆预警阿尔茨海默病[J].中国医药报,2015.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
    2019-04-09 1459d61dm64暂无昵称

    很不错

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
    2019-04-09 smartxiuxiu

    有趣

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
    2019-04-09 飛歌

    学习了很有用不错

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
    2019-04-09 深海的鱼

    学习学习学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2075660, encodeId=4a6920e5660ff, content=<a href='/topic/show?id=0d6d954207a' target=_blank style='color:#2F92EE;'>#都挺好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95420, encryptionId=0d6d954207a, topicName=都挺好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Tue Feb 25 12:13:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402778, encodeId=988d1402e7808, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Wed Apr 10 14:13:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364344, encodeId=3c15364344ba, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d3385074475, createdName=1459d61dm64暂无昵称, createdTime=Tue Apr 09 07:16:17 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364343, encodeId=296d36434384, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Tue Apr 09 07:05:42 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364342, encodeId=9c733643428c, content=学习了很有用不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 09 07:01:16 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364338, encodeId=19d936433892, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Apr 09 05:46:20 CST 2019, time=2019-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364332, encodeId=71d636433286, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 08 23:37:44 CST 2019, time=2019-04-08, status=1, ipAttribution=)]
    2019-04-08 orangesking

    0

相关资讯

Science:阿尔茨海默病30年谜底揭晓!关键蛋白作用被发现!

阿尔茨海默病(AD)是严重危及中老年人身心健康的中枢神经系统退变性疾病,目前对其发病机制的认识以β-淀粉样蛋白(Aβ)学说占主导地位。然而,最近几十年国际上所有针对Aβ的靶向性药物基本均告失败,导致相关研究停滞不前。近日,比利时VIB研究所的研究人员破解了一个隐藏了30年的秘密,Aβ的前体蛋白—淀粉样前体蛋白(APP)竟然存在我们不曾知晓的作用途径!而这条途径或许正是AD患者神经元养护、缓解症状的

Mol Psychiatry:实锤了!高胆碱饮食可抗击阿尔茨海默病!

有学者指出,中国正逐步走进老龄化社会,退行性病变明显增多,神经变性疾病已成为四大死因之一,阿尔茨海默病(AD)则是老年人神经变性疾病的最常见类型。其中,家族性阿尔茨海默病(FAD)患者起病更早、进展迅速、病情更严重,而根治之法的问世却不知何年何月。近日,亚利桑那州立大学生命科学学院的研究人员指出,长期高胆碱饮食竟然可以有效改善FAD!而且该治疗效应还可以延续至下一代!这为神经变性疾病的表观遗传

Diabetes Care:治疗状况对2型糖尿病与阿尔茨海默病关系的重要性

由此可见,治疗状态可能改变2型糖尿病与阿尔茨海默病生物标志物谱和痴呆风险之间的关系。UD与tau病理学升高和痴呆风险相关,而TD则不然。虽然这项研究是观察性研究,因此无法推断因果关系,但研究结果支持治疗状态对与2型糖尿病相关阿尔茨海默病风险的潜在价值。

BMJ:绝经后激素治疗与阿尔茨海默病的风险

由此可见,长期使用全身激素治疗可能伴随着阿尔茨海默病的总体风险增加,这与孕激素类型或全身激素治疗开始时的年龄无关。相比之下,阴道雌二醇的使用没有这种风险。尽管阿尔茨海默病的绝对风险增加很小,但该研究的数据应该为当前和未来激素治疗的女性提供决策信息。

Autophagy:阿尔茨海默病治疗研究进展

3月22日,中国科学院昆明动物研究所姚永刚课题组在阿尔茨海默病的治疗研究中取得新进展,相关成果以Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model为题,发表在Autophagy上。该研究阐明了核受体过氧化物酶体α

抗炎药物对预防阿尔茨海默病无效

几十年来,研究人员已经知道炎症伴随着阿尔茨海默病(AD)脑部病变。一些早期研究表明,"超级阿司匹林"或非甾体类抗炎药(NSAID)可以避免AD发生。然而,在临床试验显示NSAIDs对已经患有AD的患者治疗无效,因此医生们在进一步临床试验中去评价这些药物是否对有AD发病风险的人起到预防作用。