JAHA:儿童重症监护病房的重症儿童心肺复苏的流行病学特征

2021-04-28 MedSci原创 MedSci原创

这项来自英国的多中心研究数据为进一步研究提供了基础,并为预防PICU心脏骤停提供了基准和质量改进的证据。

心肺骤停是儿科重症监护病房(PICUs)死亡率和发病率的主要因素。了解心肺复苏(CPR)的流行病学和危险因素可能会为国家质量改进计划提供参考。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员使用从儿童重症监护审计网络数据库中前瞻性收集的数据进行回顾性队列分析。儿科重症监护审核网络数据库纳入了英国所有PICU患儿数据。

研究人员确定了英格兰(2013-2017年)23个重症监护病房中接受过CPR的儿童,并分析了CPR的发生率和相关因素。研究人员使用Logistic回归来估计关联的大小和精确度。

5年内68114例入院患者的CPR累积发生率为2.2%,4.9次/1000床/日。心血管诊断(比值比[OR]为2.30;95%CI为2.02-2.61)、年龄<1岁(OR为1.84;95%CI为1.65-2.04)、入院时儿童死亡率指数2得分(OR为1.045;95%CI为1.042–1.047)和更长的住院时间(OR为1.013;95%CI为1.012–1.014)与接受CPR的几率增加相关。研究人员还发现入院前心脏骤停史(OR为20.69;95%CI为18.16-23.58)以及入住非心脏PICU的心脏病患儿(OR为2.75;95%CI为1.91–3.98)与较高的CPR风险相关。黑人(OR为1.68;95%CI为1.36–2.07)和亚洲裔(OR为1.49;95%CI为1.28–1.74)儿童在PICU中接受CPR的风险高于白人儿童。

由此可见,这项来自英国的多中心研究数据为进一步研究提供了基础,并为预防PICU心脏骤停提供了基准和质量改进的证据

原始出处:

Khurram Mustafa.et al.Epidemiology of Cardiopulmonary Resuscitation in Critically Ill Children Admitted to Pediatric Intensive Care Units Across England: A Multicenter Retrospective Cohort Study.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.018177

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  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411385, encodeId=c84b141138532, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Apr 30 13:45:38 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551200, encodeId=087d155120004, content=<a href='/topic/show?id=e2c1e230796' target=_blank style='color:#2F92EE;'>#监护#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72307, encryptionId=e2c1e230796, topicName=监护)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=477814173963, createdName=bioon6, createdTime=Fri Apr 30 13:45:38 CST 2021, time=2021-04-30, status=1, ipAttribution=)]
    2021-04-30 zhaohui6731
  6. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411385, encodeId=c84b141138532, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Apr 30 13:45:38 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551200, encodeId=087d155120004, content=<a href='/topic/show?id=e2c1e230796' target=_blank style='color:#2F92EE;'>#监护#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72307, encryptionId=e2c1e230796, topicName=监护)], attachment=null, authenticateStatus=null, createdAvatar=null, 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    2021-04-30 lizhou0204
  7. 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  8. 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