Hypertension:压力反射激活治疗高血压长期效果如何?

2017-03-21 xing.T MedSci原创

经过6年的随访,压力反射激活疗法在没有主要安全问题的情况下,可以有效地持续降低顽固性高血压患者诊室血压。

压力反射激活疗法是治疗顽固性高血压的一种新技术。虽然短期的研究已经证明它能够降低血压,但其长期结果尚未有报道。近日,血管权威杂志Hypertension上发表了一篇研究文章,研究人员旨在评估压力反射激活疗法的长期疗效和安全性。

研究人员对只要被纳入了3个以难治性高血压患者为研究对象的研究中的其中一个的所有患者的长期随访数据进行了分析。该研究共对383例患者进行分析:其中143名参与者已经完成了5年的随访,另外48名患者完成了6年的随访。

在整个队列中,诊室收缩压从179±24mmHg下降到了144±28 mmHg(P<0.0001),而诊室舒张压从103±16mmHg下降到了85±18 mm Hg(P<0.0001)。心率从74±15次每分钟下降到71±13次每分钟(P<0.02)。在心衰患者中,压力反射激活疗法的效果要大于平均值,而在单纯性收缩期高血压患者中,压力反射激活疗法的效果要低于平均值。在约25%的患者中,压力反射激活疗法可以减少药物的数量,从平均的6个降为平均3个。无论是外科手术或血管不稳定,暂时性的副作用确实有发生,但他们不需要特殊的措施予以治疗,可以随着时间的推移而消失。

经过6年的随访,压力反射激活疗法在没有主要安全问题的情况下,可以有效地持续降低顽固性高血压患者诊室血压。

原始出处:

Peter W. de Leeuw, et al. Sustained Reduction of Blood Pressure With Baroreceptor Activation Therapy Results of the 6-Year Open Follow-Up.Hypertension. 2017. https://doi.org/10.1161/HYPERTENSIONAHA.117.09086

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    2018-02-13 feather89
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    2017-03-23 Ljm1998

    学习下什么是压力反射疗法

    0

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    2017-03-22 大爰

    学习并分享了谢谢!

    0