J Glaucoma:视神经乳头倾斜对近视正常眼压青光眼视野缺损的影响

2019-01-18 MedSci MedSci原创

韩国三星医疗中心眼科的Choi JH等人近日在J Glaucoma杂志上发表了一篇重要的研究论文,他们研究了视神经乳头(ONH)倾斜是否与近视、正常眼压性青光眼(NTG)中的视野(VF)缺陷有关。

韩国三星医疗中心眼科的Choi JH等人近日在J Glaucoma杂志上发表了一篇重要的研究论文,他们研究了视神经乳头(ONH)倾斜是否与近视、正常眼压性青光眼(NTG)中的视野(VF)缺陷有关。

他们在双侧近视NTG中较少和更高的VF缺陷组之间,进行变量比较。使用眼底摄影和光谱域(SD)光学相干断层扫描(OCT)等方法测量垂直、水平、最大ONH倾斜角和最大ONH倾斜的角位置。并进行逻辑回归分析以评估与双侧近视NTG中更高程度的VF缺陷相关的变量。

他们总共对包括112名患有双侧近视NTG患者进行了研究。水平ONH倾斜角与最大ONH倾斜角位置之间存在显着的相关性(R = 0.45,P <0.001)。在逻辑回归分析中,较大数量的药物、较大水平ONH倾斜和较大的ONH倾斜角位置与近视NTG中更高程度的VF缺陷相关(分别为P = 0.004; P = 0.014; P = 0.037)。VF缺陷的位置与水平ONH倾斜方向和最大ONH倾斜的角位置相关(kappa = 0.63,P <0.001; kappa = 0.48,P <0.001)。

因此,他们认为,水平ONH倾斜和最大ONH倾斜角位置与近视NTG眼中VF缺陷的严重程度和位置相关。

原文出处:

Choi, J.H., J.C. Han, and C. Kee, The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Inter-eye Comparison Study. J Glaucoma, 2019.

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    2019-06-04 gj0740
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    2019-04-07 aliceclz
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    2019-01-20 swallow
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    2019-01-19 一个字-牛

    学习了谢谢分享

    0

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