J Neurointerv Surg:脑膜中动脉栓塞术可作为症状性慢性硬膜下血肿手术的辅助疗法

2020-12-16 MedSci原创 MedSci原创

慢性硬膜下血肿(CSDH)常需要手术干预进行治疗,然而,15%的病例在治疗后的1年出现复发。近些年,脑膜中动脉(MMA)栓塞术成为预防CSDH复发的一种潜在疗法。

慢性硬膜下血肿(CSDH)常需要手术干预进行治疗,然而,15%的病例在治疗后的1年出现复发。近些年,脑膜中动脉(MMA)栓塞术成为预防CSDH复发的一种潜在疗法。

 

近日,一项发表于BMJ题为“Middle meningeal artery embolization as an adjuvant treatment to surgery for symptomatic chronic subdural hematoma: a pilot study assessing hematoma volume resorption”的文章探讨MMA栓塞对有症状患者术后血肿体积重吸收(HVR)的影响。

2018年4月至2018年10月,对需要手术的 46名CSDH参与者进行前瞻性随机化,接受单独的手术治疗(ST组)或手术联合辅助MMA栓塞(ST+MMAE组)。主要结果是3个月CT扫描上测量的HVR与栓塞前即时CT扫描的比较。次要结果是CSDH的临床复发和安全性事件。

 

最终41名患者实现了3个月的随访。21名患者接受了MMA栓塞术。3个月时,ST+MMAE组术后HVR的水平较高(平均差异17.5 mL,95% CI 3.87至31.16 mL;p=0.015)。两名参与者出现CSDH复发(每组一名)。一名患者死亡(ST组)。没有MMA栓塞相关不良事件的报告。

综上所述,该研究结果表明,手术干预联合MMA栓塞可使患者术后3个月CSDH重吸收增加。每组均有1例CSDH复发的报告,但无治疗相关并发症的报告。

 

原始出处:

 

Sam Ng, Imad Derraz, et al., Middle meningeal artery embolization as an adjuvant treatment to surgery for symptomatic chronic subdural hematoma: a pilot study assessing hematoma volume resorption. J Neurointerv Surg. 2020 Jul;12(7):695-699. doi: 10.1136/neurintsurg-2019-015421.

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