2019ESC:诺华公司的Entresto将心衰住院率和心血管死亡率降低了13%

2019-09-02 Allan MedSci原创

诺华公司在周日(2019年9月1日)举行的欧洲心脏病学会(ESC)年会上展示了III期PARAGON-HF试验的详细结果,证明Entresto(sacubitril / valsartan)显著减少了射血分数保留型心力衰竭(HFpEF)患者的心衰住院率和心血管死亡率(降低了13%)。

诺华公司在周日(201991日)举行的欧洲心脏病学会(ESC)年会上展示了IIIPARAGON-HF试验的详细结果,证明Entrestosacubitril / valsartan)显著减少了射血分数保留型心力衰竭(HFpEF)患者的心衰住院率和心血管死亡率(降低了13%)。

PARAGON-HF共招募了4822HFpEF患者,这些患者随机接受每天两次的Entresto或缬沙坦。诺华公司表示,Entresto对某些亚组的主要终点显示出更明显的影响,包括中位射血分数为57%或更低的患者,Entresto将这些患者的心衰风险/血管死亡风险减少了22%。


原始出处:

http://www.firstwordpharma.com/node/1663114#axzz5yLsSdZlS

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    2019-11-26 zhouqu_8
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