BMJ子刊:别再“躺平”了!快来看看这份超重或肥胖对心肺适能(CRF)的影响报告!

2022-01-18 MedSci原创 MedSci原创

研究证明了低体能与多种心脏代谢因素之间存在强烈的负性相关,包括肥胖(整体和腹部)、高血压和代谢综合征以及心脏保护药物的使用。

心肺适能(CRF)代表身体将氧气从大气输送到线粒体的能力,以及细胞利用氧气进行身体机能活动的能力,因此被认为是全身健康的标志。有证据表明,低 CRF 可能是死亡率的强预测因子。还有机制研究表明,2型糖尿病与低心肺适应性(CRF)独立相关。然而关于2型糖尿病中CRF的情况知之甚少,本研究评估了超重/肥胖的2型糖尿病成人与低CRF的相关性。

在这项前瞻性研究中,共有4215名患有2型糖尿病且无心血管疾病的参与者进行了最大运动测试。低CRF的定义基于健美操中心纵向研究参考标准。通过问卷调查来评估卡路里摄入量和身体活动。使用双能x线骨密度仪评估体脂肪组成。

结果显示,腰围、收缩压、血糖指数、全身脂肪、热量摄入和脂肪量与健康呈负相关。与中等或高CRF组相比,低CRF组肥胖的腹部肥胖(男性3.99,女性为2.28)、高血压(男性1.74,女性1.44)、代谢综合征(男性5.52,女性为2.25)、使用β受体阻滞剂(男性1.22,女性1.33)、使用ACE抑制剂和血管紧张素受体阻滞剂(男性1.86,女性1.07)的几率更大。有意思的是还发现了CRF较低的女性当前吸烟的几率较高。

前瞻性研究中2型糖尿病的健康和性别十分位数调整平均值

低健康状态的参与者按性别调整选定相关性的优势比:在男性和女性中,体质差的人更容易出现腹部肥胖、代谢综合征

总而言之,研究证明了低体能与多种心脏代谢因素之间存在强烈的负性相关,包括肥胖(整体和腹部)、高血压和代谢综合征以及心脏保护药物的使用。此外,较低的健康状况与女性较高的卡路里摄入量、较低的体力活动水平以及较高的全身脂肪有关。

 参考文献:Kaze ADAgoons DDSanthanam P, et al. Correlates of cardiorespiratory fitness among overweight or obese individuals with type 2 diabetes.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2081278, encodeId=c36b20812e832, content=<a href='/topic/show?id=2bac52049b' target=_blank style='color:#2F92EE;'>#CRF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5204, encryptionId=2bac52049b, topicName=CRF)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sun Oct 16 17:08:13 CST 2022, time=2022-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1684585, encodeId=99b21684585b7, content=<a href='/topic/show?id=dfae5133e1d' target=_blank style='color:#2F92EE;'>#心肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51337, encryptionId=dfae5133e1d, topicName=心肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8e128082444, createdName=aids222, createdTime=Sun Feb 13 06:08:13 CST 2022, time=2022-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849360, encodeId=87b4184936062, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Jul 29 23:08:13 CST 2022, time=2022-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974232, encodeId=4d0c19e4232d8, content=<a href='/topic/show?id=bcbe9293912' target=_blank style='color:#2F92EE;'>#超重或肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92939, encryptionId=bcbe9293912, topicName=超重或肥胖)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Jan 02 07:08:13 CST 2023, time=2023-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515030, encodeId=2c8415150303f, content=<a href='/topic/show?id=3545513e044' target=_blank style='color:#2F92EE;'>#心肺适能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51370, encryptionId=3545513e044, topicName=心肺适能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55b110706669, createdName=1508842480_96220440, createdTime=Tue Jan 18 06:08:13 CST 2022, time=2022-01-18, status=1, ipAttribution=)]
    2022-10-16 仁心济世
  2. [GetPortalCommentsPageByObjectIdResponse(id=2081278, encodeId=c36b20812e832, content=<a href='/topic/show?id=2bac52049b' target=_blank style='color:#2F92EE;'>#CRF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5204, encryptionId=2bac52049b, topicName=CRF)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sun Oct 16 17:08:13 CST 2022, time=2022-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1684585, encodeId=99b21684585b7, content=<a href='/topic/show?id=dfae5133e1d' target=_blank style='color:#2F92EE;'>#心肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51337, encryptionId=dfae5133e1d, topicName=心肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8e128082444, createdName=aids222, createdTime=Sun Feb 13 06:08:13 CST 2022, time=2022-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849360, encodeId=87b4184936062, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Jul 29 23:08:13 CST 2022, time=2022-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974232, encodeId=4d0c19e4232d8, content=<a href='/topic/show?id=bcbe9293912' target=_blank style='color:#2F92EE;'>#超重或肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92939, encryptionId=bcbe9293912, topicName=超重或肥胖)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Jan 02 07:08:13 CST 2023, time=2023-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515030, encodeId=2c8415150303f, content=<a href='/topic/show?id=3545513e044' target=_blank style='color:#2F92EE;'>#心肺适能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51370, encryptionId=3545513e044, topicName=心肺适能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55b110706669, createdName=1508842480_96220440, createdTime=Tue Jan 18 06:08:13 CST 2022, time=2022-01-18, status=1, ipAttribution=)]
    2022-02-13 aids222
  3. [GetPortalCommentsPageByObjectIdResponse(id=2081278, encodeId=c36b20812e832, content=<a href='/topic/show?id=2bac52049b' target=_blank style='color:#2F92EE;'>#CRF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5204, encryptionId=2bac52049b, topicName=CRF)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sun Oct 16 17:08:13 CST 2022, time=2022-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1684585, encodeId=99b21684585b7, content=<a href='/topic/show?id=dfae5133e1d' target=_blank style='color:#2F92EE;'>#心肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51337, encryptionId=dfae5133e1d, topicName=心肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8e128082444, createdName=aids222, createdTime=Sun Feb 13 06:08:13 CST 2022, time=2022-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849360, encodeId=87b4184936062, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Jul 29 23:08:13 CST 2022, time=2022-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974232, encodeId=4d0c19e4232d8, content=<a href='/topic/show?id=bcbe9293912' target=_blank style='color:#2F92EE;'>#超重或肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92939, encryptionId=bcbe9293912, topicName=超重或肥胖)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Jan 02 07:08:13 CST 2023, time=2023-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515030, encodeId=2c8415150303f, content=<a href='/topic/show?id=3545513e044' target=_blank style='color:#2F92EE;'>#心肺适能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51370, encryptionId=3545513e044, topicName=心肺适能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55b110706669, createdName=1508842480_96220440, createdTime=Tue Jan 18 06:08:13 CST 2022, time=2022-01-18, status=1, ipAttribution=)]
    2022-07-29 gaoxiaoe
  4. [GetPortalCommentsPageByObjectIdResponse(id=2081278, encodeId=c36b20812e832, content=<a href='/topic/show?id=2bac52049b' target=_blank style='color:#2F92EE;'>#CRF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5204, encryptionId=2bac52049b, topicName=CRF)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sun Oct 16 17:08:13 CST 2022, time=2022-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1684585, encodeId=99b21684585b7, content=<a href='/topic/show?id=dfae5133e1d' target=_blank style='color:#2F92EE;'>#心肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51337, encryptionId=dfae5133e1d, topicName=心肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8e128082444, createdName=aids222, createdTime=Sun Feb 13 06:08:13 CST 2022, time=2022-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849360, encodeId=87b4184936062, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Jul 29 23:08:13 CST 2022, time=2022-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974232, encodeId=4d0c19e4232d8, content=<a href='/topic/show?id=bcbe9293912' target=_blank style='color:#2F92EE;'>#超重或肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92939, encryptionId=bcbe9293912, topicName=超重或肥胖)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Jan 02 07:08:13 CST 2023, time=2023-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515030, encodeId=2c8415150303f, content=<a href='/topic/show?id=3545513e044' target=_blank style='color:#2F92EE;'>#心肺适能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51370, encryptionId=3545513e044, topicName=心肺适能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55b110706669, createdName=1508842480_96220440, createdTime=Tue Jan 18 06:08:13 CST 2022, time=2022-01-18, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2081278, encodeId=c36b20812e832, content=<a href='/topic/show?id=2bac52049b' target=_blank style='color:#2F92EE;'>#CRF#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5204, encryptionId=2bac52049b, topicName=CRF)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sun Oct 16 17:08:13 CST 2022, time=2022-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1684585, encodeId=99b21684585b7, content=<a href='/topic/show?id=dfae5133e1d' target=_blank style='color:#2F92EE;'>#心肺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51337, encryptionId=dfae5133e1d, topicName=心肺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c8e128082444, createdName=aids222, createdTime=Sun Feb 13 06:08:13 CST 2022, time=2022-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849360, encodeId=87b4184936062, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Jul 29 23:08:13 CST 2022, time=2022-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974232, encodeId=4d0c19e4232d8, content=<a href='/topic/show?id=bcbe9293912' target=_blank style='color:#2F92EE;'>#超重或肥胖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92939, encryptionId=bcbe9293912, topicName=超重或肥胖)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Jan 02 07:08:13 CST 2023, time=2023-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1515030, encodeId=2c8415150303f, content=<a href='/topic/show?id=3545513e044' target=_blank style='color:#2F92EE;'>#心肺适能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51370, encryptionId=3545513e044, topicName=心肺适能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55b110706669, createdName=1508842480_96220440, createdTime=Tue Jan 18 06:08:13 CST 2022, time=2022-01-18, status=1, ipAttribution=)]

相关资讯

JAMA:中国糖尿病及糖尿病前期患病率已过50%!肥胖及超重是重要危险因素

去年夏天,“杨天真切胃”一度登上热搜。作为娱乐圈知名经纪人,杨天真在社交平台向网友宣告,为了治疗糖尿病,她选择进行“切胃”手术。

致女性不孕风险翻倍,罪魁祸首竟或是......打鼾?

PLOS ONE:阻塞性睡眠呼吸暂停增加女性不孕风险:一项14年全省人口为基础的研究

减肥降糖调脂护肝哪家强?传统糖尿病饮食&低碳水化合物饮食大PK!

Diabetologia:饮食碳水化合物限制可增强2型糖尿病患者的减重诱导的血糖控制和肝脂肪改善:一项随机对照试验

接着吃来接着摇!好吃好玩还低卡的Ta,还能调血脂血糖抗氧化!

Nutrition & Metabolism:食用红海藻石花菜(Campylaephora hypnaeoides J. Agardh)通过抑制氧化应激和炎症反应减轻小鼠肥胖和相关代谢紊乱

Diabetes:尽管肥胖但机体的代谢状况依然很健康,秘密竟然是...

与机体中没有棕色脂肪的肥胖人群相比,严重超重(肥胖)的人群机体或许也含有活跃的棕色脂肪,这就提示其机体新陈代谢或许更健康,而且使用的能量也更多。

柳叶刀子刊:接种不积极,胖子更易出问题!超30万人数据揭示BMI与新冠重症关联!

Lancet Reg Health Am. :为什么肥胖青年应该优先参与COVID-19疫苗接种计划?一项全国性的回顾性研究