BMJ子刊:别再“躺平”了!快来看看这份超重或肥胖对心肺适能(CRF)的影响报告!

2022-01-18 MedSci原创 MedSci原创

研究证明了低体能与多种心脏代谢因素之间存在强烈的负性相关,包括肥胖(整体和腹部)、高血压和代谢综合征以及心脏保护药物的使用。

心肺适能(CRF)代表身体将氧气从大气输送到线粒体的能力,以及细胞利用氧气进行身体机能活动的能力,因此被认为是全身健康的标志。有证据表明,低 CRF 可能是死亡率的强预测因子。还有机制研究表明,2型糖尿病与低心肺适应性(CRF)独立相关。然而关于2型糖尿病中CRF的情况知之甚少,本研究评估了超重/肥胖的2型糖尿病成人与低CRF的相关性。

在这项前瞻性研究中,共有4215名患有2型糖尿病且无心血管疾病的参与者进行了最大运动测试。低CRF的定义基于健美操中心纵向研究参考标准。通过问卷调查来评估卡路里摄入量和身体活动。使用双能x线骨密度仪评估体脂肪组成。

结果显示,腰围、收缩压、血糖指数、全身脂肪、热量摄入和脂肪量与健康呈负相关。与中等或高CRF组相比,低CRF组肥胖的腹部肥胖(男性3.99,女性为2.28)、高血压(男性1.74,女性1.44)、代谢综合征(男性5.52,女性为2.25)、使用β受体阻滞剂(男性1.22,女性1.33)、使用ACE抑制剂和血管紧张素受体阻滞剂(男性1.86,女性1.07)的几率更大。有意思的是还发现了CRF较低的女性当前吸烟的几率较高。

前瞻性研究中2型糖尿病的健康和性别十分位数调整平均值

低健康状态的参与者按性别调整选定相关性的优势比:在男性和女性中,体质差的人更容易出现腹部肥胖、代谢综合征

总而言之,研究证明了低体能与多种心脏代谢因素之间存在强烈的负性相关,包括肥胖(整体和腹部)、高血压和代谢综合征以及心脏保护药物的使用。此外,较低的健康状况与女性较高的卡路里摄入量、较低的体力活动水平以及较高的全身脂肪有关。

 参考文献:Kaze ADAgoons DDSanthanam P, et al. Correlates of cardiorespiratory fitness among overweight or obese individuals with type 2 diabetes.

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    2022-10-16 仁心济世
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    2022-02-13 aids222
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    2022-07-29 gaoxiaoe
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