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每周一次的somapacitan治疗生长激素缺乏症儿童，效果与每日一次的生长激素相当

2019-09-23 Allan MedSci原创

生长激素缺乏症somapacitanGHD
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诺和诺德（Novo Nordisk）近日宣布，每周一次的新型生长激素衍生物somapacitan治疗生长激素缺乏症（GHD）儿童，与每天一次的Norditropin®（生长激素）的有效性、安全性和耐受性相当。

诺和诺德（Novo Nordisk）近日宣布，每周一次的新型生长激素衍生物somapacitan治疗生长激素缺乏症（GHD）儿童，与每天一次的Norditropin®（生长激素）的有效性、安全性和耐受性相当。LarsSävendahl教授在欧洲小儿内分泌学会（ESPE）第58届年会上介绍了来自REAL 3 II期试验的最新数据。 

REAL 3试验比较了每周一次的somapacitan（0.04、0.08或0.16 mg / kg / day）与每日一次的生长激素（0.034 mg / kg / day）治疗GHD儿童的差异。1年的结果支持了先前报告的6个月的数据，其中一项新发现是somapacitan（0.16mg / kg /day）组患儿的年平均身高生长速度（HV，cm / year）显著高于生长激素组。


原始出处：

http://www.firstwordpharma.com/node/1668250#axzz60IsjKrMi

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    2019-12-07 ms6980045490879608

    #somapacitan#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1947291, encodeId=793b194e29172, content=<a href='/topic/show?id=c3fe16544d4' target=_blank style='color:#2F92EE;'>#somapacitan#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16544, encryptionId=c3fe16544d4, topicName=somapacitan)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLx96cCLjNYsHar1XErTVibOydfEC9iaYgrXp3SicXwntSAEDeQAlM2vLqTfm6oPORxaib3UIgyHQJJ7A/132, createdBy=36f02500138, createdName=ms6980045490879608, createdTime=Sat Dec 07 01:24:00 CST 2019, time=2019-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1738565, encodeId=36111e3856584, content=<a href='/topic/show?id=a9dd4e63c4' target=_blank style='color:#2F92EE;'>#CIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4763, encryptionId=a9dd4e63c4, topicName=CIT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eabf34462441, createdName=12498877m109暂无昵称, createdTime=Wed Oct 23 15:24:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798616, encodeId=07a01e9861615, content=<a href='/topic/show?id=03386963456' target=_blank style='color:#2F92EE;'>#生长激素缺乏症儿童#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69634, encryptionId=03386963456, topicName=生长激素缺乏症儿童)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Sun Jan 12 21:24:00 CST 2020, time=2020-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1338197, encodeId=02ae133819e9b, content=<a href='/topic/show?id=cd2a262068' target=_blank style='color:#2F92EE;'>#APA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2620, encryptionId=cd2a262068, topicName=APA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce072500140, createdName=12498b3em08(暂无昵称), createdTime=Wed Sep 25 02:24:00 CST 2019, time=2019-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407467, encodeId=37b4140e46721, content=<a href='/topic/show?id=a79569632f4' target=_blank style='color:#2F92EE;'>#生长激素缺乏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69632, encryptionId=a79569632f4, topicName=生长激素缺乏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3fa2654160, createdName=lidong41, createdTime=Wed Sep 25 02:24:00 CST 2019, time=2019-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046914, encodeId=21d31046914df, content=疗效只是效果的众多方面之一，还要看对患者的获益，包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Mon Sep 23 14:24:00 CST 2019, time=2019-09-23, status=1, ipAttribution=)]
    2019-10-23 12498877m109暂无昵称

    #CIT#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1947291, encodeId=793b194e29172, content=<a href='/topic/show?id=c3fe16544d4' target=_blank style='color:#2F92EE;'>#somapacitan#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16544, encryptionId=c3fe16544d4, topicName=somapacitan)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLx96cCLjNYsHar1XErTVibOydfEC9iaYgrXp3SicXwntSAEDeQAlM2vLqTfm6oPORxaib3UIgyHQJJ7A/132, createdBy=36f02500138, createdName=ms6980045490879608, createdTime=Sat Dec 07 01:24:00 CST 2019, time=2019-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1738565, encodeId=36111e3856584, content=<a href='/topic/show?id=a9dd4e63c4' target=_blank style='color:#2F92EE;'>#CIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4763, encryptionId=a9dd4e63c4, topicName=CIT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eabf34462441, createdName=12498877m109暂无昵称, createdTime=Wed Oct 23 15:24:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798616, encodeId=07a01e9861615, content=<a href='/topic/show?id=03386963456' target=_blank style='color:#2F92EE;'>#生长激素缺乏症儿童#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69634, encryptionId=03386963456, topicName=生长激素缺乏症儿童)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Sun Jan 12 21:24:00 CST 2020, time=2020-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1338197, encodeId=02ae133819e9b, content=<a href='/topic/show?id=cd2a262068' target=_blank style='color:#2F92EE;'>#APA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2620, encryptionId=cd2a262068, topicName=APA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce072500140, createdName=12498b3em08(暂无昵称), createdTime=Wed Sep 25 02:24:00 CST 2019, time=2019-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407467, encodeId=37b4140e46721, content=<a href='/topic/show?id=a79569632f4' target=_blank style='color:#2F92EE;'>#生长激素缺乏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69632, encryptionId=a79569632f4, topicName=生长激素缺乏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3fa2654160, createdName=lidong41, createdTime=Wed Sep 25 02:24:00 CST 2019, time=2019-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046914, encodeId=21d31046914df, content=疗效只是效果的众多方面之一，还要看对患者的获益，包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Mon Sep 23 14:24:00 CST 2019, time=2019-09-23, status=1, ipAttribution=)]
    2020-01-12 sunyl07

    #生长激素缺乏症儿童#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1947291, encodeId=793b194e29172, content=<a href='/topic/show?id=c3fe16544d4' target=_blank style='color:#2F92EE;'>#somapacitan#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16544, encryptionId=c3fe16544d4, topicName=somapacitan)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLx96cCLjNYsHar1XErTVibOydfEC9iaYgrXp3SicXwntSAEDeQAlM2vLqTfm6oPORxaib3UIgyHQJJ7A/132, createdBy=36f02500138, createdName=ms6980045490879608, createdTime=Sat Dec 07 01:24:00 CST 2019, time=2019-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1738565, encodeId=36111e3856584, content=<a href='/topic/show?id=a9dd4e63c4' target=_blank style='color:#2F92EE;'>#CIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4763, encryptionId=a9dd4e63c4, topicName=CIT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eabf34462441, createdName=12498877m109暂无昵称, createdTime=Wed Oct 23 15:24:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798616, encodeId=07a01e9861615, content=<a href='/topic/show?id=03386963456' target=_blank style='color:#2F92EE;'>#生长激素缺乏症儿童#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69634, encryptionId=03386963456, topicName=生长激素缺乏症儿童)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Sun Jan 12 21:24:00 CST 2020, time=2020-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1338197, encodeId=02ae133819e9b, content=<a href='/topic/show?id=cd2a262068' target=_blank style='color:#2F92EE;'>#APA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2620, encryptionId=cd2a262068, topicName=APA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce072500140, createdName=12498b3em08(暂无昵称), createdTime=Wed Sep 25 02:24:00 CST 2019, time=2019-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407467, encodeId=37b4140e46721, content=<a href='/topic/show?id=a79569632f4' target=_blank style='color:#2F92EE;'>#生长激素缺乏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69632, encryptionId=a79569632f4, topicName=生长激素缺乏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3fa2654160, createdName=lidong41, createdTime=Wed Sep 25 02:24:00 CST 2019, time=2019-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046914, encodeId=21d31046914df, content=疗效只是效果的众多方面之一，还要看对患者的获益，包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Mon Sep 23 14:24:00 CST 2019, time=2019-09-23, status=1, ipAttribution=)]
    2019-09-25 12498b3em08(暂无昵称)

    #APA#

    0

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    2019-09-25 lidong41

    #生长激素缺乏#

    0

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    2019-09-23 CHANGE

    疗效只是效果的众多方面之一，还要看对患者的获益，包括生活质量等因素共同决定效果的

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