Eur Radiol:你再管不住嘴,恐怕腿都迈不动了!——体重增加与关节退变的相关性

2017-11-02 shaosai MedSci原创

本研究旨在评价48个月体重改变与半月板退变(MID)进展的相关性,并将结果发表在Eur Radiol上。

本研究旨在评价48个月体重改变与半月板退变(MID)进展的相关性,并将结果发表在Eur Radiol上。

本研究共纳入了487例有MID的患者,并在基线和48月后行3T MRI检查(扫描方案一致,包括压脂和非压脂的FSE序列)。受试者中有体重下降(≥3%, n = 141)、体重中度增加(3-10%, n = 77)、体重明显增加(>10%, n = 15)和体重保持不变(n = 254)。利用WORMS分级系统评价MID进展甚至半月板撕裂,并利用Logistic回归在各体重变化组进行分析。ANOVA和卡方检验分析受试者特点。

体重减轻到体重明显增加的受试者中MID均发生进展,但在体重中(OR=4.9; 95% CI:2.4-8.9)重(OR, 9.5; 95% CI 3.2-28.5)度增加的受试者中较体重保持不变的受试者格外明显。在体重中(内侧半月板: OR, 6.8; 95% CI 3.5-11.3; 外侧半月板: OR, 2.6; 95% CI 1.1-6.6)重(内侧半月板: OR, 21.0; 95% CI 5.1-80.7; 外侧半月板: OR, 9.7; 95% CI 0.95-100.2)度增加的受试者中两侧半月板结果相似。

本研究表明,体重增加与半月板退变具有相关性。体重增加越明显,半月板退变的风险更大。

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    2017-11-04 1201e5c5m39暂无昵称

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    2017-11-02 惠映实验室

    学习了.谢谢.

    0

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