Arch Phys Med Rehabil:运动训练对老年痴呆症患者的治疗作用

2020-08-15 MedSci原创 MedSci原创

本研究旨在探究力量或有氧训练是否可以为老年痴呆症患者的日常生活活动提供更多的好处,以及确定运动对认知、抑郁和生化指标的影响。

本研究旨在探究力量或有氧训练是否可以为老年痴呆症患者的日常生活活动提供更多的好处,以及确定运动对认知、抑郁和生化指标的影响。

采用单盲随机对照试验 单盲随机对照试验设计,在退伍军人的养老院纳入80名迷你精神状态检查的分数在15到26分之间志愿者。由于11名参与者存在心肺或骨科疾病禁止运动训练,以及可能阻碍回答我们问卷内容的认知问题,因此被排除。在运动训练期间,有8名参与者自愿退出研究。

将剩余参与者随机分配进行力量或有氧训练,共4周。主要结果是Barthel指数。其他结果测量包括迷你精神状态检查、蒙特利尔认知评估、老年抑郁量表、血浆单核细胞趋化蛋白-1水平、胰岛素样生长因子-1水平和血清脑源性神经营养因子水平。

结果显示,在完成该项目后,力量训练组患者的巴特尔指数,迷你精神状态检查,蒙特利尔认知评估,和血浆单核细胞化学活性蛋白-1水平得到显著改善。对于接受过有氧训练的患者,他们的血清脑源性神经营养因子也有明显改善。然而,关于这些结果措施的改善程度两组之间没有达到明显的统计学差异。

综上所述,该研究结果表明,通过4个月的强化训练,脑源性神经营养因子得到了明显的改善,但关于这些结果指标的改善程度在两组之间没有达到显著的统计学差异。该研究表明,无论是力量训练还是有氧训练,为期4周的强化运动计划都能为老年痴呆症患者带来显著的益处,而通过有氧训练,血清中的脑源性神经营养因子也得到了额外的改善。

原始出处:

I-Ting LiuWei-Ju Lee, et al., Therapeutic Effects of Exercise Training on Elderly Patients With Dementia: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2020 May;101(5):762-769. doi: 10.1016/j.apmr.2020.01.012. 

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    2020-08-17 qjddjq
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    2020-08-17 Jessica

    运动会给#老年痴呆症#患者带来一些好处,同时也会改善血清中的脑源性神经营养因子。#运动#是良医。

    0

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    2020-08-16 junJUN

    老年人痴呆何药可用??

    0

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