Arthritis Rheumatol:美国痛风和高尿酸血症的当代患病率及十年趋势

2019-01-08 xiangting MedSci原创

在这个具有全国代表性的美国成人样本中,痛风和高尿酸血症的患病率在过去十年中仍然保持不变。

这项研究使用最新和既往有全国代表性的美国男性、女性样本(国家健康与营养检查调查[NHANES] 2007-2016),估算了美国痛风和高尿酸血症的当代患病率及其十年趋势,以及痛风患者中降尿酸疗法(ULT)的流行率。 

使用NHANES 2015-2016的5,467名参与者的数据,研究人员估算了痛风和高尿酸血症的最新患病率。在NHANES时,所有参与者被问及由医疗专业人士诊断的痛风病史和用药史。高尿酸血症定义为男性血清尿酸盐水平> 7.0mg/dL,女性血清尿酸盐水平> 5.7mg/dL。研究人员使用来自NHANES 2007-2016的数据分析了这些估算的十年趋势,使用NHANES 2007-14(迄今为止的最新数据)分析了ULT使用趋势。

2015-2016年美国成人的痛风患病率为3.9%(920万)(男性和女性分别为5.2%[590万]和2.7%[330万])。男性平均血清尿酸盐水平为6.0mg/dL,女性为4.8mg/dL,高尿酸血症的患病率分别为20.2%和20.0%。痛风和高尿酸血症的患病率在过去十年中保持稳定(P趋势>0.05)。2007年至2014年期间,痛风患者中ULT的流行率为33%,并随时间的推移保持稳定(P趋势>0.05)。

在这个具有全国代表性的美国成人样本中,痛风和高尿酸血症的患病率在过去十年中仍然保持不变。尽管有这种疾病,只有三分之一的痛风患者正在接受ULT治疗。

原始出处:

Michael Chen‐Xu. Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey 2007‐2016. Arthritis Rheumatol. 07 January 2019.

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    2019-06-09 一个字-牛

    学习了谢谢分享

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    2019-01-10 zhaojie88
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