AHA/ASA自发性脑出血指南:外科和康复治疗要点

2015-06-05 大鹏 译 医学论坛网

美国心脏学会和美国卒中学会(AHA/ASA)近期于《卒中》杂志发布了关于自发性脑内出血(ICH)的详细指南,本文为外科和康复治疗等要点。 脑出血(ICH)外科手术治疗 1.若患者存在脑出血,同时存在神经功能恶化或由于脑室梗塞引发的脑干受压(可存在脑积水),则尽可能早的接受血肿手术切除(Ⅰ,B)。对于此类患者,不推荐将脑室引流优先度置于手术治疗之前

美国心脏学会和美国卒中学会(AHA/ASA)近期于《卒中》杂志发布了关于自发性脑内出血(ICH)的详细指南,本文为外科和康复治疗等要点。

脑出血(ICH)外科手术治疗

1.若患者存在脑出血,同时存在神经功能恶化或由于脑室梗塞引发的脑干受压(可存在脑积水),则尽可能早的接受血肿手术切除(Ⅰ,B)。对于此类患者,不推荐将脑室引流优先度置于手术治疗之前(Ⅲ,B)。

2.对于占多数的幕上ICH患者,不确定外科手术治疗是否有效(Ⅱb,A,指南新修改内容)。

3.与患者出现症状恶化再行血肿清除术相比,早期血肿清除术并不能带来更多治疗收益。(Ⅱb,A,指南新内容)

4.对于症状恶化的患者,幕上血肿清除术可作为一项挽救生命的措施。(Ⅱb,C,指南新内容)

5.若幕上ICH患者存在昏迷、血肿大病灶伴明显中线转移,或ICH患者存在药物难治性颅内压升高,去骨瓣减压术伴或不伴血肿清除术或降低其死亡率。(Ⅱb,C,指南新内容)

6.尚不确定采用立体定向抽吸术或内窥镜抽吸术的微创血块清除术(可伴血栓清除)疗效。(Ⅱb,B,指南新修改内容)

预后评估

1.推荐ICH出现后进行早期积极治疗,且延迟不复苏预嘱至患者住院期第二天结束(Ⅱa,B,指南新修改内容),但已有不复苏预嘱的患者不适用该条建议。现行ICH后早期的预测模型会由于治疗中断或早期不复苏预嘱而出现偏差。除非患者有明确意见,否则不复苏预嘱不能限制药物或手术治疗。(Ⅲ,C,指南新修改内容)

康复治疗

1.考虑到ICH预后进展为残疾的多样性及复杂性,推荐所有ICH患者接受多学科综合康复治疗。(Ⅰ,A,指南新修改内容)

2.如果条件允许,应尽早开展改善预后的康复治疗,并完善无缝治疗程序,加快出院进程及以家庭为主的治疗,从而加速患者康复进程。(Ⅱa,B)

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    2016-05-03 ly17291850

    关键问题就在于神经康复/修复类药物开发的滞后

    0

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    2016-05-19 lvygwyt2781
  3. [GetPortalCommentsPageByObjectIdResponse(id=83606, encodeId=76088360623, content=关键问题就在于神经康复/修复类药物开发的滞后, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63d51718849, createdName=ly17291850, createdTime=Tue May 03 12:27:00 CST 2016, time=2016-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858434, encodeId=f18e1858434a4, content=<a href='/topic/show?id=efd52810cc' target=_blank style='color:#2F92EE;'>#ASA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2810, encryptionId=efd52810cc, topicName=ASA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=947269, createdName=lvygwyt2781, createdTime=Thu May 19 21:30:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267260, encodeId=e28e126e2609a, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389397, encodeId=8be7138939e8f, content=<a href='/topic/show?id=61f086095c1' target=_blank style='color:#2F92EE;'>#自发性脑出血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86095, encryptionId=61f086095c1, topicName=自发性脑出血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=606c2500035, createdName=ms3153534357578991, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530521, encodeId=9c24153052136, content=<a href='/topic/show?id=ed4a860e872' target=_blank style='color:#2F92EE;'>#自发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86078, encryptionId=ed4a860e872, topicName=自发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=584a12117168, createdName=sodoo, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26163, encodeId=f61726163d7, content=脑出血的治疗除掉手术之外确实没有太大的进展, ,至少短期内也没有什么特效药, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Sat Jun 06 13:11:00 CST 2015, time=2015-06-06, status=1, ipAttribution=)]
    2015-06-07 zhaohui6731
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  5. [GetPortalCommentsPageByObjectIdResponse(id=83606, encodeId=76088360623, content=关键问题就在于神经康复/修复类药物开发的滞后, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63d51718849, createdName=ly17291850, createdTime=Tue May 03 12:27:00 CST 2016, time=2016-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858434, encodeId=f18e1858434a4, content=<a href='/topic/show?id=efd52810cc' target=_blank style='color:#2F92EE;'>#ASA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2810, encryptionId=efd52810cc, topicName=ASA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=947269, createdName=lvygwyt2781, createdTime=Thu May 19 21:30:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267260, encodeId=e28e126e2609a, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389397, encodeId=8be7138939e8f, content=<a href='/topic/show?id=61f086095c1' target=_blank style='color:#2F92EE;'>#自发性脑出血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86095, encryptionId=61f086095c1, topicName=自发性脑出血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=606c2500035, createdName=ms3153534357578991, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530521, encodeId=9c24153052136, content=<a href='/topic/show?id=ed4a860e872' target=_blank style='color:#2F92EE;'>#自发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86078, encryptionId=ed4a860e872, topicName=自发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=584a12117168, createdName=sodoo, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26163, encodeId=f61726163d7, content=脑出血的治疗除掉手术之外确实没有太大的进展, ,至少短期内也没有什么特效药, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Sat Jun 06 13:11:00 CST 2015, time=2015-06-06, status=1, ipAttribution=)]
    2015-06-07 sodoo
  6. [GetPortalCommentsPageByObjectIdResponse(id=83606, encodeId=76088360623, content=关键问题就在于神经康复/修复类药物开发的滞后, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63d51718849, createdName=ly17291850, createdTime=Tue May 03 12:27:00 CST 2016, time=2016-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858434, encodeId=f18e1858434a4, content=<a href='/topic/show?id=efd52810cc' target=_blank style='color:#2F92EE;'>#ASA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2810, encryptionId=efd52810cc, topicName=ASA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=947269, createdName=lvygwyt2781, createdTime=Thu May 19 21:30:00 CST 2016, time=2016-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267260, encodeId=e28e126e2609a, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389397, encodeId=8be7138939e8f, content=<a href='/topic/show?id=61f086095c1' target=_blank style='color:#2F92EE;'>#自发性脑出血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86095, encryptionId=61f086095c1, topicName=自发性脑出血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=606c2500035, createdName=ms3153534357578991, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530521, encodeId=9c24153052136, content=<a href='/topic/show?id=ed4a860e872' target=_blank style='color:#2F92EE;'>#自发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86078, encryptionId=ed4a860e872, topicName=自发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=584a12117168, createdName=sodoo, createdTime=Sun Jun 07 00:30:00 CST 2015, time=2015-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26163, encodeId=f61726163d7, content=脑出血的治疗除掉手术之外确实没有太大的进展, ,至少短期内也没有什么特效药, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Sat Jun 06 13:11:00 CST 2015, time=2015-06-06, status=1, ipAttribution=)]
    2015-06-06 lovetcm

    脑出血的治疗除掉手术之外确实没有太大的进展, ,至少短期内也没有什么特效药

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