女性幼年期患注意缺陷多动障碍,则成年后肥胖风险大

2016-02-05 QQduhp 译 MedSci原创

在过去30年里,儿童和成人肥胖的发病率大幅上升,且有证据表明这与注意缺陷多动障碍(ADHD)明显相关。 既往研究已经表明,由于潜在的行为学、神经生物学和遗传机制等因素,ADHD和肥胖之间密切相关。 ADHD儿童易冲动和注意力不集中等行为因素会导致他们饮食不规律。 遗传和神经生物学因素可导致患儿多巴胺分泌系统或脑源性嗜神经因子(BDNF)分泌出现障碍。 既往研究指出,共同的病因学可能导致ADHD患儿

在过去30年里,儿童和成人肥胖的发病率大幅上升,且有证据表明这与注意缺陷多动障碍(ADHD)明显相关。 


既往研究已经表明,由于潜在的行为学、神经生物学和遗传机制等因素,ADHD和肥胖之间密切相关。 

ADHD儿童易冲动和注意力不集中等行为因素会导致他们饮食不规律。 遗传和神经生物学因素可导致患儿多巴胺分泌系统或脑源性嗜神经因子(BDNF)分泌出现障碍。 

既往研究指出,共同的病因学可能导致ADHD患儿肥胖和多动症共同进展。患儿营养过剩增加其ADHD风险,认知过度导致儿童肥胖。
 
梅奥诊所的Seema Kumar博士等研究人员开展了一项以人群为基础的纵向研究,以探究男性和女性患ADHD和肥胖之间的关系。 

研究人员对336名生于1976-1982年、儿童时期患有ADHD的民众进行了探究,同时他们也与665名未患有ADHD、同一年龄段和性别的健康成人作为对照。

研究人员从1976-2010年的相关医疗记录汇总收集患者的体重、身高和兴奋剂治疗等信息,并使用Cox模型来评估多动症和肥胖之间的联系。 

结果表明,儿童期患有ADHD的女性的肥胖风险是未患ADHD女性的2倍。似乎没有联系肥胖和兴奋剂治疗儿童多动症儿童的案件。 

Kumar博士认为,儿童时患有ADHD的女性成年后患肥胖症的风险增加,用于治疗ADHD的兴奋剂药物并不改变这一风险。Kumar博士呼吁民众增加风险意识,以防止女性ADHD患者变得肥胖。研究人员鼓励ADHD患者转移注意力,开始健康和积极的生活。 

下一步,该研究小组计划调查ADHD患者的精神并发症及其对民众肥胖发展的影响。

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    2016-02-12 1de3b290m83(暂无匿称)

    疾病的联系

    0

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    2016-02-07 忠诚向上

    有用

    0

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    2016-02-07 忠诚向上

    好好学习

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