J Clin Periodontol:瑟瑟发抖!慢性牙周炎或可导致勃起功能障碍!

2018-05-07 MedSci MedSci原创

本研究旨在校正生物标志物和其他合并症后确定慢性牙周炎与勃起功能障碍之间的关系。纳入158名男性患者进行病例对照研究。根据国际勃起功能指数,80例勃起功能障碍患者,78例对照者。收集社会人口学资料并进行牙周检查。评估睾酮、血脂谱、C-反应蛋白和血糖参数。所有变量进行组间比较,并进行多因素logistic回归分析。结果显示,74%的病例诊断为慢性牙周炎。病例组探诊深度4-6 mm(p = 0.05)和

本研究旨在校正生物标志物和其他合并症后确定慢性牙周炎与勃起功能障碍之间的关系。

纳入158名男性患者进行病例对照研究。根据国际勃起功能指数,80例勃起功能障碍患者,78例对照者。收集社会人口学资料并进行牙周检查。评估睾酮、血脂谱、C-反应蛋白和血糖参数。所有变量进行组间比较,并进行多因素logistic回归分析。

结果显示,74%的病例诊断为慢性牙周炎。病例组探诊深度4-6 mm(p = 0.05)和临床附着丧失> 3 mm的位点较高(p <0.01)。此外,病例组甘油三酯(p <0.01)、C-反应蛋白(p = 0.02)和糖化血红蛋白(p = 0.04)也较高。Logistic回归分析显示,慢性牙周炎患者更易发生勃起功能障碍(OR = 2.17; 95%CI(1.06-4.43); P = 0.03),与其他混杂因素无关。

综上所述,该研究结果表明,勃起功能障碍患者的牙周状况更差。慢性牙周炎是勃起功能障碍的一个独立危险因素,在其发病机制中起着关键作用。

原始出处:


Martín A, Bravo M, et al., Chronic periodontitis is associated to erectile dysfunction. A case-control study in european population. J Clin Periodontol. 2018 May 3. doi: 10.1111/jcpe.12909. 

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    2018-08-24 feather89
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    2018-08-02 habb
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1727276, encodeId=e8861e2727664, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Aug 24 21:28:00 CST 2018, time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771144, encodeId=50961e7114431, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Thu Aug 02 14:28:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368661, encodeId=d3661368661e5, content=<a href='/topic/show?id=0e30535657b' target=_blank style='color:#2F92EE;'>#慢性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53565, encryptionId=0e30535657b, topicName=慢性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c64275, createdName=piaojinhua, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421157, encodeId=4f9a142115e8f, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450868, encodeId=f917145086896, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502723, encodeId=efeb1502e23ae, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312954, encodeId=6d68312954ad, content=综上所述.该研究结果表明.勃起功能障碍患者的牙周状况更差.慢性牙周炎是勃起功能障碍的一个独立危险因素.在其发病机制中起着关键作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 07 22:19:16 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1727276, encodeId=e8861e2727664, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Aug 24 21:28:00 CST 2018, time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771144, encodeId=50961e7114431, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Thu Aug 02 14:28:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368661, encodeId=d3661368661e5, content=<a href='/topic/show?id=0e30535657b' target=_blank style='color:#2F92EE;'>#慢性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53565, encryptionId=0e30535657b, topicName=慢性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c64275, createdName=piaojinhua, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421157, encodeId=4f9a142115e8f, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450868, encodeId=f917145086896, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502723, encodeId=efeb1502e23ae, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312954, encodeId=6d68312954ad, content=综上所述.该研究结果表明.勃起功能障碍患者的牙周状况更差.慢性牙周炎是勃起功能障碍的一个独立危险因素.在其发病机制中起着关键作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 07 22:19:16 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1727276, encodeId=e8861e2727664, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Aug 24 21:28:00 CST 2018, time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771144, encodeId=50961e7114431, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Thu Aug 02 14:28:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368661, encodeId=d3661368661e5, content=<a href='/topic/show?id=0e30535657b' target=_blank style='color:#2F92EE;'>#慢性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53565, encryptionId=0e30535657b, topicName=慢性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c64275, createdName=piaojinhua, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421157, encodeId=4f9a142115e8f, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450868, encodeId=f917145086896, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502723, encodeId=efeb1502e23ae, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Wed May 09 10:28:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312954, encodeId=6d68312954ad, content=综上所述.该研究结果表明.勃起功能障碍患者的牙周状况更差.慢性牙周炎是勃起功能障碍的一个独立危险因素.在其发病机制中起着关键作用., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 07 22:19:16 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-07 有备才能无患

    综上所述.该研究结果表明.勃起功能障碍患者的牙周状况更差.慢性牙周炎是勃起功能障碍的一个独立危险因素.在其发病机制中起着关键作用.

    0

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Electron Physician:吸烟对慢性牙周炎患者牙龈组织炎症细胞浸润亚型的影响

背景慢性牙周炎患者血液和龈沟液检测表明,吸烟会增加细胞因子的产生。目的评估吸烟和非吸烟受试者牙周炎和健康组织单核炎症细胞浸润免疫标记物的表达。方法该病例对照研究选取了2016年转诊到伊朗马什哈德牙科学院牙周病诊所的41名患者。参与者全部为伊朗Khorasanian人,年龄在35-65岁之间。通过常规牙周瓣手术获得牙龈活检。使用免疫组织化学进行CD20,CD3,CD68和CD45RO标记物检测。使用

J Periodontal Res:有无牙周疾病史患者的牙龈生物型

本研究旨在确定有无牙周病史患者的牙龈生物型。

J Clin Periodontol:一个纤溶酶原下游单倍型块与慢性侵袭性牙周炎相关

已知纤溶酶原基因(PLG)中的内含子变体rs4252120与侵袭性牙周炎(AgP)和动脉粥样硬化有关。此次我们研究了跨PLG的染色体区域与慢性牙周炎(CP)和AgP的关联。

J Periodontol:信号调节蛋白激酶/蛋白激酶B-p53-BH3–结构域凋亡诱导蛋白通路调节成骨细胞牙龈素诱导的细胞凋亡

牙龈素是由牙龈卟啉单胞菌(慢性牙周炎中的主要病原体)产生的半胱氨酸蛋白酶。本研究旨在检测牙龈素在促进成骨细胞凋亡中的作用。

J Periodontal Res:甘氨酸粉末空气抛光作为慢性牙周炎患者非手术牙周治疗方法的效果

甘氨酸粉末空气抛光(GPAP)是去除龈下菌斑生物膜以进行有效牙周治疗的替代方法。本研究旨在探讨龈下GPAP作为慢性牙周炎患者非手术牙周治疗方法的效果。招募了二十七名不吸烟的受试者。将每个受试者的两个象限随机分配,根据分口设计,在探诊深度≥5mm的部位进行洁治和根面平整(SRP)和GPAP(试验组)或SRP和空气冲洗(对照组)。在基线和治疗后1、3和6个月测量龈沟液的临床参数,包括龈沟液量和白细胞介

J Periodontol:健康人与慢性牙周炎、心肌梗死患者内皮功能的比较

重度牙周病患者内皮细胞会有损害,内皮功能的破坏有助于动脉粥样硬化斑块的形成,进而可能成为冠状动脉疾病的风险。本研究的目的是通过血管舒张功能(FMD)评估牙周健康和疾病中的内皮功能。