同济医院开设白血病停药门诊

2017-05-17 佚名 健康报

尽管靶向药物治疗慢性粒细胞白血病效果较好,但长期的药费给不少家庭带来沉重负担。近日,华中科技大学同济医学院附属同济医院开设停药门诊,有望帮助慢性粒细胞白血病患者实现停止服药。

尽管靶向药物治疗慢性粒细胞白血病效果较好,但长期的药费给不少家庭带来沉重负担。近日,华中科技大学同济医学院附属同济医院开设停药门诊,有望帮助慢性粒细胞白血病患者实现停止服药。

慢性粒细胞白血病是一种起源于人体造血干细胞的恶性疾病,成人白血病中20%是此种类型。目前,医学治疗主要是服用小分子靶向药物,长期无病生存率可达90%。尽管药物控制疗效良好,但是患者需长期服药,每月药费高达2万元~4万元。而且,约1/3的长期服药者会发生骨痛、腹泻、皮疹等并发症。因此,国内外均将停止服药后保持无疾病状态作为慢性粒细胞白血病治疗的终极目标。

同济医院血液内科主任周剑峰及其团队,对符合停药条件的患者进行停药观察,经过4年临床研究,已为18位患者实现完全停药。目前,全世界仅有法国与澳大利亚具有权威的慢性粒细胞白血病停药研究数据。同济医院血液科的研究数据与他们基本一致:停止治疗后,约40%的患者保持缓解,疾病未出现复发;而复发患者重新服药后,99%能够达到停药前疗效,未出现疾病进展等严重结果。

与国际研究同步后,研究人员还对比分析了复发患者与非复发患者干细胞的差异,寻找导致复发的核心因素并有针对性地设计干预措施,有望提前“锁定”停药后复发人群,更精准地实现停药。

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    2017-05-19 yinhl1980
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    2017-05-18 139****5926

    好文章学习了

    0

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    2017-05-18 榄枷檬

    谢谢分享

    0

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    2017-05-18 龙胆草

    学习了,谢谢分享

    0

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    2017-05-17 138****8908

    太棒了,这样减少了患者的经济负担

    0

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    2017-05-17 Chongyang Zhang

    签到学习了很多。

    0

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