县级医院心梗患者病死率高,高龄多、病情重、再灌注率低是主因

2019-12-07 文韬 中国循环杂志

中国农村居民急性心梗死亡率快速上升,增速远超城市居民。为此,CAMI 研究重点比较了省部级、地市级医院和县级医院收治的急性ST 段抬高性心肌梗死(STEMI) 的患者特征、治疗手段以及预后的差异。

在海峡心血管病高峰论坛上,中国医学科学院阜外医院杨进刚医生报告了中国急性心肌梗死注册(CAMI)研究的部分结果。

中国农村居民急性心梗死亡率快速上升,增速远超城市居民。为此,CAMI 研究重点比较了省部级、地市级医院和县级医院收治的急性ST 段抬高性心肌梗死(STEMI) 的患者特征、治疗手段以及预后的差异。

CAMI 研究发现,县级医院收治的患者普遍比省部级和地市级医院患者年龄大,病情重。

虽然县级医院就诊的患者能够在发病3 小时内到达医院的比例高达43.8%。但相比于省、市级医院, 县级医院再灌注治疗率仍明显较低。

就导致不同级别医院死亡率有较大差别,尤其是killip 分级较高的患者,县医院Killip 4 级的患者死亡率接近50%。

研究还发现,心力衰竭/ 休克是我国心梗患者住院死亡的第一位原因,可能与再灌注率低有关。

另外,尽管县级医院收治的心衰患者较多,但利尿剂和醛固酮拮抗剂应用比例反而较低,这可能反应了县级医院对心梗后心衰的处理经验不足。

研究还发现,超过3 小时患者才接受溶栓的患者,在校正混淆变量后,2 年随访复合终点事件(包括全因死亡、心肌梗死和脑卒中)的发生率未优于未接受再灌注治疗患者。

CAMI 研究还分析了80 家医院29 581 例STEMI 患者的医疗质量,发现STEMI 患者救治医院的较高医疗质量与住院死亡率较低有关。与较高医疗质量的医院相比,中等医疗质量医院的住院死亡率增加11%,较低医疗质量医院住院死亡率增加30%。

他介绍,之前北京安贞医院赵冬教授发现,对于我国院内急性心肌梗死的治疗,如果联合应用所有院内心肌梗死最佳治疗策略,仅仅能将中国冠心病总病死率降低9.6%。

这些措施包括应用4种最有效的口服药物和氯吡格雷,NSTEMI 患者应用肝素三级医院接受急诊介入治疗,而在二级医院溶栓等。这是因为中国患者普遍到达医院较晚,不能从再灌注治疗中获益。

因此,“加强患者教育,缩短从发病到再灌注时间,加强心肌梗死的救治的无缝链接,才能从根本上解决问题。”

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2049507, encodeId=9a9c204950eaa, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Feb 21 22:12:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677414, encodeId=2ff616e7414a5, content=<a href='/topic/show?id=0101e089022' target=_blank style='color:#2F92EE;'>#病死率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70890, encryptionId=0101e089022, topicName=病死率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4da27497284, createdName=soongzhihua, createdTime=Mon Apr 27 19:12:00 CST 2020, time=2020-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661098, encodeId=37e7166109899, content=<a href='/topic/show?id=9b713e32568' target=_blank style='color:#2F92EE;'>#县级医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37325, encryptionId=9b713e32568, topicName=县级医院)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a43325187210, createdName=pps20027, createdTime=Sun Dec 15 13:12:00 CST 2019, time=2019-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765088, encodeId=c2b31e6508863, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Oct 24 15:12:00 CST 2020, time=2020-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416103, encodeId=61481416103e6, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Mon Dec 09 13:12:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2049507, encodeId=9a9c204950eaa, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Feb 21 22:12:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677414, encodeId=2ff616e7414a5, content=<a href='/topic/show?id=0101e089022' target=_blank style='color:#2F92EE;'>#病死率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70890, encryptionId=0101e089022, topicName=病死率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4da27497284, createdName=soongzhihua, createdTime=Mon Apr 27 19:12:00 CST 2020, time=2020-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661098, encodeId=37e7166109899, content=<a href='/topic/show?id=9b713e32568' target=_blank style='color:#2F92EE;'>#县级医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37325, encryptionId=9b713e32568, topicName=县级医院)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a43325187210, createdName=pps20027, createdTime=Sun Dec 15 13:12:00 CST 2019, time=2019-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765088, encodeId=c2b31e6508863, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Oct 24 15:12:00 CST 2020, time=2020-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416103, encodeId=61481416103e6, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Mon Dec 09 13:12:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2049507, encodeId=9a9c204950eaa, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Feb 21 22:12:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677414, encodeId=2ff616e7414a5, content=<a href='/topic/show?id=0101e089022' target=_blank style='color:#2F92EE;'>#病死率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70890, encryptionId=0101e089022, topicName=病死率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4da27497284, createdName=soongzhihua, createdTime=Mon Apr 27 19:12:00 CST 2020, time=2020-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661098, encodeId=37e7166109899, content=<a href='/topic/show?id=9b713e32568' target=_blank style='color:#2F92EE;'>#县级医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37325, encryptionId=9b713e32568, topicName=县级医院)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a43325187210, createdName=pps20027, createdTime=Sun Dec 15 13:12:00 CST 2019, time=2019-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765088, encodeId=c2b31e6508863, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Oct 24 15:12:00 CST 2020, time=2020-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416103, encodeId=61481416103e6, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Mon Dec 09 13:12:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2049507, encodeId=9a9c204950eaa, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Feb 21 22:12:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677414, encodeId=2ff616e7414a5, content=<a href='/topic/show?id=0101e089022' target=_blank style='color:#2F92EE;'>#病死率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70890, encryptionId=0101e089022, topicName=病死率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4da27497284, createdName=soongzhihua, createdTime=Mon Apr 27 19:12:00 CST 2020, time=2020-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661098, encodeId=37e7166109899, content=<a href='/topic/show?id=9b713e32568' target=_blank style='color:#2F92EE;'>#县级医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37325, encryptionId=9b713e32568, topicName=县级医院)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a43325187210, createdName=pps20027, createdTime=Sun Dec 15 13:12:00 CST 2019, time=2019-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765088, encodeId=c2b31e6508863, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Oct 24 15:12:00 CST 2020, time=2020-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416103, encodeId=61481416103e6, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Mon Dec 09 13:12:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2049507, encodeId=9a9c204950eaa, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Feb 21 22:12:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677414, encodeId=2ff616e7414a5, content=<a href='/topic/show?id=0101e089022' target=_blank style='color:#2F92EE;'>#病死率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70890, encryptionId=0101e089022, topicName=病死率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4da27497284, createdName=soongzhihua, createdTime=Mon Apr 27 19:12:00 CST 2020, time=2020-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661098, encodeId=37e7166109899, content=<a href='/topic/show?id=9b713e32568' target=_blank style='color:#2F92EE;'>#县级医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37325, encryptionId=9b713e32568, topicName=县级医院)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a43325187210, createdName=pps20027, createdTime=Sun Dec 15 13:12:00 CST 2019, time=2019-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765088, encodeId=c2b31e6508863, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sat Oct 24 15:12:00 CST 2020, time=2020-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416103, encodeId=61481416103e6, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Mon Dec 09 13:12:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
    2019-12-09 xlysu

相关资讯

江西提高县级医院服务能力

近日,江西省卫生计生委印发《江西省县级综合医院医疗服务能力建设工作方案》提出,通过建设、培训、支援等方式,以人才、技术、重点专科为核心,加强县级综合医院医疗服务能力建设。

“双标准”提升县级中医院能力

近日,国家中医药管理局印发《县级中医医院医疗服务能力基本标准(试行)》和《县级中医医院医疗服务能力推荐标准(试行)》。

全面提升县级医院综合能力工作方案提出

近日,国家卫生健康委发布《关于印发全面提升县级医院综合能力工作方案(2018-2020年)的通知》。

入局康复护理 县级医院崛起新机遇已到来

6月5日,国务院办公厅发布《深化医药卫生体制改革2019年重点工作任务》(下称“2019医改重点工作任务”)。健康界对36项重点工作加以梳理后发现,政策对各级各类医疗机构如何实现“分兵把口”且“合纵连横”,已作出清晰规划。对于上级医疗机构,下一步倡导的发展方向是希望其主动调整门诊病种结构,逐步扩大日间手术病种,发挥“带头”作用;通过学科建设提升服务能力,则成为县级医疗机构的首要任务。各级各类医疗机

第四十八次风险提示性公告,又一家医疗租赁模式公司或将崩盘

近日,中信建投第四十八次发布关于珠海市蓝海之略医疗股份有限公司(以下简称蓝海之略)的风险提示性公告,公告显示蓝海之略存在几个重大风险事项,具体包括涉及重大未决诉讼仲裁;重大债务违约等财务风险;主要资产被查封、扣押、冻结;停产、批产清算等经营风险;重大亏损、损失或承担重大赔偿责任;公司及关联方涉嫌违法违规;公司未能规范履行信息披露义务。

300家县级医院达到县级医院综合服务能力推荐标准要求 它们都是谁?

2014年,原国家卫生计生委和国家中医药局联合印发了《全面提升县级医院综合能力工作方案》(国卫医发〔2014〕48号),启动了第一阶段全面提升县级医院综合能力工作。各地按照我委统一部署,认真组织开展相关工作。经过三年的能力建设,全国300家县级医院已基本达到县级医院综合服务能力推荐标准要求(以下简称达标县医院)。现将达标县医院名单印发给你们,要在进一步加强达标县医院能力建设的同时,发挥其示范带