Diabetic Med:根据糖尿病诊断年龄,非洲裔美国人和美国白人1型糖尿病患者的成年后期死亡率

2018-10-29 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于根据糖尿病诊断年龄,非洲裔美国人和美国白人1型糖尿病患者的成年后期死亡率的研究。研究为估计社会经济地位较低非洲裔美国人和美国白人的总体和原因特定死亡率,并同时检查是否因糖尿病发病年龄不同而有任何过度风险。 研究人员使用南部社区队列研究,对一组年龄在40-79岁(平均50岁)的大多数低收入参与者进行了死亡率随访,其中包括在30岁之前

近日,国际杂志 《Diabetic Med》上在线发表一项关于根据糖尿病诊断年龄,非洲裔美国人和美国白人1糖尿病患者的成年后期死亡率的研究。研究为估计社会经济地位较低非洲裔美国人和美国白人的总体和原因特定死亡率,并同时检查是否因糖尿病发病年龄不同而有任何过度风险。

研究人员使用南部社区队列研究,对一组年龄在40-79岁(平均50岁)的大多数低收入参与者进行了死亡率随访,其中包括在30岁之前诊断出胰岛素治疗的糖尿病(n=475)和没有糖尿病(n = 62 266)。儿童期发病被定义为在20岁之前诊断出的糖尿病(n=162),而年轻-成年期发病被定义为在2029岁之间诊断出的糖尿病(n = 313)。特定原因的死亡率是从死亡记录获得的潜在死因和致死原因。进行多变量Cox分析。

在随访期间(平均9.5年),38.7%的患者和12.9%的非糖尿病患者死亡。与没有糖尿病的人相比,儿童和青年期-成年糖尿病患者死亡率的增加与以下因素有关:全因(童年:风险比4.3CI 3.3-5.5;青年期:风险比4.9 CI 4.0-5.8; 缺血性心脏病(儿童:风险比5.7CI 3.5-9.4;青年期:风险比7.9CI 5.6-11.0; 心力衰竭(儿童:风险比7.3CI 4.2-12.7;青年期:风险比5.4CI 3.3-8.9; 败血症(儿童:风险比10.3CI 6.1-17.3;青年期:风险比8.8CI 5.7-13.5; 肾衰竭(儿童:危险比15.1CI 8.6-26.5;青年期:危险比18.2CI 12.3-27.1; 呼吸系统疾病(儿童:风险比3.9CI 2.3-6.7;青年期:风险比5.3CI 3.7-7.7; 自杀/凶杀/事故(儿童:风险比2.3CI 0.72-7.0;青年期:风险比5.8CI 3.4-10.2; 和癌症(儿童:风险比2.1CI 0.98-4.4;青年期:风险比1.2CI 0.55-2.5)。

研究人员在早期胰岛素治疗非洲裔美国人和美国白人糖尿病患者中观察到全因,肾功能衰竭,缺血性心脏病和心力衰竭的过高超长期死亡率。

原始出处:

B. N. Conway, M. F. LopesVirella, W. J. Blot. Late adulthood mortality among AfricanAmerican and white American people with Type 1 diabetes according to age at diabetes diagnosis

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  4. 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    2019-05-05 仁心济世
  5. 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  6. 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  7. 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    2018-10-29 misszhang

    谢谢MedSci提供最新的资讯

    0

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Diabetic Med:客户和医疗保健专业人员的视角看1型糖尿病患者饮食失调

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Fiasp可有效控制1型糖尿病患者的血糖水平

在第44届国际儿科和青少年糖尿病学会年会上发布的最新数据显示,与传统门冬胰岛素相比,接受Fiasp(门冬胰岛素的超快速作用配方)的研究人群的总体血糖水平(HbA1c)降低幅度更大。

EASD 2014:我国1型糖尿病患者自身抗体阳性率调查结果公布

中山大学附属第三医院翁建平教授等在EASD 2014年会上公布了我国1型糖尿病患者自身抗体阳性率调查结果:我国成人1型糖尿病患者的自身抗体阳性率低于1型糖尿病高发国家。抗体阳性患者的临床进展更为迅速,与糖尿病自身抗体导致β细胞功能下降更快有关。(摘要号287) 研究数据来自于广东省1型糖尿病转化医学研究,本次分析共纳入1070例1型糖尿病患者,患者平均年龄为31.7岁,平均糖尿病病程为4

Lancet Diabetes Endo:达格列净能否改善1型糖尿病患者的血糖控制

2017年发表于《Lancet Diabetes Endocrinol》上的一项多中心、双盲、3期、随机对照试验,考察了达格列净在血糖未充分控制的1型糖尿病患者中的疗效和安全性(DEPICT-1)。

Diabetic Med:关于1型糖尿病患者饮食失调,患者和医疗保健专业人员的意见如何?

近日,国际杂志 《Diabetic Med》上在线发表一项关于1型糖尿病患者饮食失调,患者和医疗保健专业人员的意见的研究。探讨1型糖尿病患者和饮食失调患者以及医疗保健专业人员对其进行治疗的经验,通过了解双方的经验为未来医疗服务的发展提供依据。 研究人员从饮食失调糖尿病患者协会(英国国家慈善机构)和专业网络招募参与者。9名部分/完全康复的1型糖尿病饮食障碍患者和8名医疗保健专业人员参加了由医学