Stroke:COVID-19患者急性缺血性脑卒中的特点

2021-03-18 MedSci原创 MedSci原创

与AIS/不伴有COVID-19的患者相比,AIS/COVID-19患者年龄更小,卒中严重程度更高,评估和治疗时间更长,发病率和死亡率也更高。

近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员从458家至少有1例COVID-19病例的AIS医院中确定了在2020年2月4日至2020年6月29日期间住院的4971例患者(AIS/COVID-19:1143人;AIS/不伴有COVID-19: 40828人),并评估了受试者的临床特征、治疗方案和结局。

与AIS/不伴有COVID-19的患者相比,AIS/COVID-19患者更年轻,更有可能是非西班牙裔黑人、西班牙裔或亚裔,更有可能具有更高的美国国立卫生研究院卒中量表评分,大血管闭塞比例也更大。两组间溶栓率和取栓率相似。

AIS/COVID-19患者队列从就诊到接受计算机断层扫描(中位数为55[18-207] vs 35[14-99]分钟,P<0.001)、从就诊到穿针(59[40-82] vs 46[33-64]分钟,P<0.001)和从就诊到接受血管内治疗(114 [74-169] vs 90[54-133]分钟,P=0.002)的间隔时间更长。

在校正模型中,AIS/COVID-19患者出院时校正后的Rankin量表评分≤2的几率降低(比值比为0.65 [95%CI为0.52-0.81],P<0.001),而住院死亡的几率增加(比值比为4.34 [95%CI为3.48-5.40],P<0.001)。

由此可见,该研究表明,与AIS/不伴有COVID-19的患者相比,AIS/COVID-19患者年龄更小,卒中严重程度更高,评估和治疗时间更长,发病率和死亡率也更高。

原始出处:

Pratyaksh K. Srivastava.et al.Acute Ischemic Stroke in Patients With COVID-19.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.034301

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    2021-03-19 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2021-03-19 ms3000002051620385

    感谢分享

    0

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