J Rheumatol:类风湿性关节炎中的心血管疾病预防

2018-07-18 xiangting MedSci原创

尽管CVD和糖尿病的风险较高,RA中对一般人群糖尿病筛查指南的依从性欠佳。

这项研究旨在评估与一般人群相比,类风湿性关节炎(RA)的心血管疾病(CVD)预防糖尿病筛查指南的依从性。

研究人员对基于人群的RA队列进行了首次纵向研究,纳入1996年至2006年间不列颠哥伦比亚省的所有RA病例,并随访至2010年,与匹配的一般人群进行比较。研究人员使用行政数据,在排除既往患糖尿病的个体后,测量了对一般人群指南的遵守情况[例如,在45岁后至少每3年检测一次血浆葡萄糖(PG)]。随访分为3年资格期。依从性表示为进行≥1次PG测试时期所占的比例。使用广义估计方程模型计算RA(与一般人群相比)依从性的OR(95%CI),并根据年龄和性别进行调整。还计算了每位患者的平均依从率并使用Mann-Whitney U检验进行比较。

分析包括22,624名RA患者,共计48,724个三年资格期;一般人群中有22,579人,共计51,081个三年资格期。RA组中72.3%(SD 37%)的资格期中测量了PG,一般人群为70.4%(SD 38%)(OR 1.05,95%CI 1.02-1.09,p<0.0001)。RA个体在71.4%的资格期符合推荐的筛查指南,而一般人群为70.6%(p<0.001)。相对于一般人群,RA中的筛查随着时间得到改善。家庭医生几乎安排了所有的PG测试。

尽管CVD和糖尿病的风险较高,RA中对一般人群糖尿病筛查指南的依从性欠佳,并与一般人群的差异不大。

原始出处:

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    2018-07-20 lmm397
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    2018-07-18 惠映实验室

    学习了谢谢分享

    0

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    2018-07-18 中医痴

    学习了不错的谢谢分享

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