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JACC： 0/1-h法则在心梗的早期诊断中安全有效

2018-07-31 MedSci MedSci原创

心血管心梗诊断
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欧洲心脏协会（ESC）的通过高敏肌钙蛋白（hs-cTn）的0/1h运算法则以排除非ST段抬高型心肌梗塞（NSTEMI）的安全性一直受到质疑。本研究的目的旨在评估该0/1h运算法则的诊断价值。本研究纳入了来自6个国家的因NSTEMI症状而至急诊就医的患者，最终的诊断由2个独立的心脏学家决定，所有患者的基线hs-cTnI和hs-cTnT水平和1h水平均进行了检测，排除诊断的安全性由NSTEMI的阴性预

欧洲心脏协会（ESC）的通过高敏肌钙蛋白（hs-cTn）的0/1h运算法则以排除非ST段抬高型心肌梗塞（NSTEMI）的安全性一直受到质疑。本研究的目的旨在评估该0/1h运算法则的诊断价值。

本研究纳入了来自6个国家的因NSTEMI症状而至急诊就医的患者，最终的诊断由2个独立的心脏学家决定，所有患者的基线hs-cTnI和hs-cTnT水平和1h水平均进行了检测，排除诊断的安全性由NSTEMI的阴性预测值（NPV）表示，诊断的准确率由NSTEMI的阳性预测值表示。最终结果发现，NSTEMI的发病率为17%，在4368例检测了hs-cTnT的患者中，排除诊断的安全性为2488/2493， NPV为99.8%，诊断的准确率为572/768，PPV为74.5%。同样地，在3500例检测了hs-cTnI的患者中，排除诊断的安全性为1528/1533，NPV为99.7%，诊断的准确率为498/800，PPV为62.3%。另外，该方法在多个亚组分析中的安全性也非常好。

本研究结果显示，欧洲心脏协会的0/1h运算法则在诊断非ST段抬高型心肌梗塞中的安全性和有效性很高。

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    2018-09-29 hbwxf

    #JACC#

    0

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    2018-08-24 jyzxjiangqin

    心梗的早期诊断。

    0

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    2018-08-12 jyzxjiangqin

    心梗的早期诊断。

    0

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    2018-08-02 12498568m50暂无昵称

    #ACC#

    0

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    2018-08-02 一叶知秋

    #早期诊断#

    0

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    2018-08-01 明崖

    学习了，有用的研究

    0

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    2018-08-01 1ddf0692m34(暂无匿称)

    学习了，

    0

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    2018-08-01 张新亮1853311252142e2fm

    好文章学习了

    0

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    2018-08-01 飛歌

    厉害厉害了我的妹

    0

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    2018-08-01 1209e435m98(暂无昵称)

    学习了，谢谢分享

    0

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