没有证据表明抗病毒疗法可重新激活水痘带状疱疹病毒

2019-10-06 Allan MedSci原创

根据2019年美国传染病学会年会上发表的一项研究,尚未发现抗逆转录病毒药物(DAA)直接激活水痘带状疱疹病毒的证据。

根据2019年美国传染病学会年会上发表的一项研究,尚未发现抗逆转录病毒药物(DAA)直接激活水痘带状疱疹病毒的证据。美国食品药品监督管理局Maximilian Rohde表示:“前瞻性DAA临床试验的数据(包括13,816名受试者)证明DAA与水痘带状疱疹病毒再激活之间没有关联。观察到水痘带状疱疹病毒的再激活率较低,尤其是在低风险人群中,例如低于50岁的人群”。

研究人员分析了来自37个II/III期临床试验的数据,其中7,901例患者单独接受DAA,4,348例患者接受DAA加利巴韦林,997例接受安慰剂,327例接受DAA联合干扰素,243例接受干扰素。


原始出处:

http://www.firstwordpharma.com/node/1671985#axzz61Rlned4y

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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    2019-10-08 yahu
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