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Ann Rheum Dis：轴向脊柱关节炎ASAS分类标准中使用脊柱MRI阳性作为影像学标准的产出

2017-07-14 xiangting MedSci原创

脊柱关节炎MRI阳性脊柱影像学标准
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在两组最长症状持续时间为3年的CBP患者中，MRI-SI和X-SI患者无骶髂关节炎患者脊柱MRI阳性率很低。

这项研究旨在评估最多3年持续时间的慢性背痛（CBP）患者MRI脊柱炎症的患病率，并评估轴向脊柱关节炎(axSpA)的ASAS分类标准中加入脊柱MRI阳性作为影像标准的产率。骶髂关节（X-SI），骶髂关节MRI（MRI-SI）和MRI脊柱的基线影像由2个有经验的阅片者进行评分。患者来自于SPACE和Récentes（DESIR）队列。在整个脊柱中评估了可能提示axSpA的炎症。MRI阳性脊柱由存在≥5个炎症性病变定义。此外还测试了替代性严格性差的定义。在这项研究中，纳入来自SPACE和DESIR队列的541和650例CBP患者。X-SI和MRI-SI在SPACE队列中40/541（7％）和76/541（14％）患者发现骶髂关节炎。DESIR队列在134/650（21％）和231/650（36％）中发现骶髂关节炎。在SPACE和DESIR中，在4/541（1％）和48/650（7％）患者中观察到MRI阳性脊柱。在没有影像学骶髂关节炎的患者中，3/447（1％）（SPACE）和8/382（2％）（DESIR）患者为MRI阳性脊柱。增加MRI阳性脊柱作为影像学标准，使得每个队列中仅一名患者重新

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    2018-04-19 jiyangfei

    #SAS#

    0

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    2018-01-30 cmj8wellington

    #Dis#

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    2017-09-10 lvygwyt2781

    #ASA#

    0

  4. 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2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-18 wxl882001

    学习一下

    0

  5. 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encodeId=11e4142296e12, content=<a href='/topic/show?id=e2c531819ce' target=_blank style='color:#2F92EE;'>#分类标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31819, encryptionId=e2c531819ce, topicName=分类标准)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94d23750245, createdName=yytms, createdTime=Sun Jul 16 08:26:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222723, encodeId=934b222e2332, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sun Jul 16 01:29:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-17 wxl882001

    学习一下

    0

  6. 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encodeId=11e4142296e12, content=<a href='/topic/show?id=e2c531819ce' target=_blank style='color:#2F92EE;'>#分类标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31819, encryptionId=e2c531819ce, topicName=分类标准)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94d23750245, createdName=yytms, createdTime=Sun Jul 16 08:26:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222723, encodeId=934b222e2332, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sun Jul 16 01:29:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-16 lmm397

    #关节炎#

    0

  7. 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2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-16 fengting3

    #脊柱关节炎#

    0

  8. 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encodeId=11e4142296e12, content=<a href='/topic/show?id=e2c531819ce' target=_blank style='color:#2F92EE;'>#分类标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31819, encryptionId=e2c531819ce, topicName=分类标准)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94d23750245, createdName=yytms, createdTime=Sun Jul 16 08:26:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222723, encodeId=934b222e2332, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sun Jul 16 01:29:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-16 yytms

    #分类标准#

    0

  9. 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encodeId=11e4142296e12, content=<a href='/topic/show?id=e2c531819ce' target=_blank style='color:#2F92EE;'>#分类标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31819, encryptionId=e2c531819ce, topicName=分类标准)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=94d23750245, createdName=yytms, createdTime=Sun Jul 16 08:26:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222723, encodeId=934b222e2332, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sun Jul 16 01:29:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-16 wxl882001

    学习一下

    0

  10. 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2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222255, encodeId=829622225520, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Jul 14 17:30:35 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-14 wxl882001

    学习一下

    0

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Cimzia有望治疗中轴性脊柱关节炎

       据UCB称，certolizumab pegol（Cimzia）在3期研究中获得了顶级的结果，该研究在成年发病的活动性中轴性脊柱关节炎（AxSpA）患者中进行，这是一类炎性风湿性疾病，其中包括强直性脊柱炎（AS）。       UCB的首席医务官兼执行副总裁、教授、Iris Loew-Friedrich博

Ann Rheum Dis：新发中轴型脊柱关节炎的骶髂关节影像学进展

新发病的axSpA患者X-SIJ损伤的五年进展是有限的，但在测量误差外是真实存在的。

J Rheumatol：脊柱关节炎中抗肿瘤坏死因子使用建议的依从性

抗TNF建议的依从性对结果的影响，对所使用的依从性定义很敏感。

J Rheumatol：前葡萄膜炎和之前未诊断的脊柱关节炎的影响

AU比临床变量更影响生活质量，特别是对那些已经存在的未确诊的SpA患者。